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Overview of Methotrexate Toxicity: A Comprehensive Literature Review.

Author: AlaliGadheer H, AlenaziFoza E, AlenazyRawan H, AlhaddadZahra A, AlharthyBaidaa T, AlhulayfiDania H, AlhumaidanSarah S, AlhumaidiNidaa T, AlobaidRahaf H, AlotaibiYasmen B, AlzahraniShahad A, BaomarAbdulrahman F, DighririIbrahim M, HamedKhalid M, HumadiAdhwa'a A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Methotrexate (MTX), a widely used drug for rheumatoid arthritis and other conditions, can cause significant toxicity. Managing MTX toxicity involves careful monitoring, dose adjustments, and the use of appropriate antidotes.
Paper Details　
Original Abstract of the Article :
Methotrexate (MTX) is significantly more effective than and has a considerable advantage over placebo in patients with severe and persistent rheumatoid arthritis (RA). The drug is used to treat a variety of malignant disorders (leukemia and cancer of the lung, breast, and uterus) and ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9595261/

データ提供：米国国立医学図書館（NLM）

Methotrexate: A Powerful Tool for Rheumatoid Arthritis, But Toxicity Requires Careful Attention

Methotrexate (MTX) is a potent and effective treatment for rheumatoid arthritis (RA), but like a camel navigating a desert, it comes with its own set of challenges. This research delves into the complexities of MTX toxicity, exploring its various manifestations and strategies for managing it. The study emphasizes the importance of understanding MTX's side effects, particularly those that affect the bone marrow, lungs, kidneys, and liver. It also highlights the crucial role of early detection, appropriate monitoring, and timely interventions to mitigate the risks of MTX toxicity.

Navigating the Toxicity of Methotrexate: A Guide for Clinicians and Researchers

This research provides valuable insights into the challenges of MTX toxicity, offering a roadmap for clinicians and researchers to better understand and manage this complex issue. The study's findings emphasize the need for a careful balance between the therapeutic benefits of MTX and the potential risks of toxicity, highlighting the importance of personalized treatment plans, vigilant monitoring, and prompt interventions to ensure patient safety and well-being.

Managing the Risks: Finding the Right Path for MTX Treatment

The journey of managing RA with MTX can be a balancing act between the benefits of this powerful medication and the potential risks of toxicity. This research provides a valuable guide for navigating this complex terrain, highlighting the importance of understanding the potential side effects, implementing careful monitoring strategies, and ensuring prompt interventions to mitigate any complications. Just like a camel navigating a desert, finding the right path for MTX treatment requires vigilance, adaptability, and a commitment to ensuring patient safety and well-being.

Dr.Camel's Conclusion

This research sheds light on the complexities of MTX toxicity, highlighting the need for a thorough understanding of its potential side effects and the importance of early detection, appropriate monitoring, and timely interventions. Just like a camel navigating a desert, managing MTX treatment effectively requires a combination of knowledge, vigilance, and a commitment to ensuring patient safety and well-being.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-11-02
Further Info :

Pubmed ID

36312688

DOI: Digital Object Identifier

PMC9595261

SNS
PICO Info
in preparation
Languages

English

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