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The efficacy of nitroglycerin to prevent radial artery spasm and occlusion during and after transradial catheterization: A systematic review and meta-analysis of randomized controlled trials.

Author: AbdelazeemBasel, AbuelazmMohamed T, Al-ZeftawyMohamed A, AtefMostafa, GamalMohamed, LutzAnthony, NooriMuhammad A, SwedSarya, VolgmanAnnabelle S

Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Subcutaneous nitroglycerin during transradial catheterization was more effective than placebo in preventing radial artery spasm (RAS) and radial artery occlusion (RAO), with risk ratios of 0.57 and 0.39, respectively. Intra-arterial and topical nitroglycerin did not show statistically significant results in preventing RAS and RAO. More research is needed to compare subcutaneous and intra-arterial nitroglycerin administration.
Paper Details　
Original Abstract of the Article :
Radial artery spasm (RAS) is the most common cause of transradial access site crossover and is a common intra-procedural complication. RAS incidence can lead to radial artery occlusion (RAO) postprocedure, preventing the radial artery as a future access site. We evaluated the efficacy of nitroglycer...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9748765/

データ提供：米国国立医学図書館（NLM）

Nitroglycerin: A Potential Solution for Radial Artery Spasm

Transradial catheterization, a common procedure used for diagnosing and treating cardiovascular conditions, is often associated with complications such as radial artery spasm (RAS) and radial artery occlusion (RAO). This research investigates the effectiveness of nitroglycerin, a medication used to dilate blood vessels, in preventing these complications. The authors conducted a systematic review and meta-analysis of randomized controlled trials to evaluate the efficacy of nitroglycerin in reducing the incidence of RAS and RAO during transradial catheterization.

Navigating the Challenges of Transradial Catheterization

The study revealed that subcutaneous nitroglycerin was significantly more effective than placebo in preventing RAS and RAO during transradial catheterization. However, intra-arterial and topical nitroglycerin did not show statistically significant benefits in preventing these complications. These findings suggest that subcutaneous nitroglycerin could be a valuable tool for minimizing complications associated with transradial catheterization, potentially improving patient outcomes.

Minimizing Complications and Ensuring Patient Well-being

This research offers a potential solution for minimizing complications associated with transradial catheterization. Just as a camel adapts to the harsh desert environment, researchers are constantly seeking ways to improve medical procedures and ensure patient well-being. By understanding the effectiveness of different methods for preventing RAS and RAO, we can better optimize the safety and efficacy of this important procedure.

Dr.Camel's Conclusion

The field of cardiovascular medicine is constantly evolving, with new approaches emerging to address the complexities of heart disease. This research, like a shimmering oasis in the desert, offers a potential solution for minimizing complications associated with transradial catheterization. By exploring different strategies for preventing RAS and RAO, we can create a more comfortable and safe experience for patients undergoing this important procedure.

Date :
  1. Date Completed 2022-12-15
  2. Date Revised 2022-12-21
Further Info :

Pubmed ID

36335609

DOI: Digital Object Identifier

PMC9748765

Related Literature

Article Analysis
・Effects of nitroglycerin topical
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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