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Trends in development and quality assessment of pharmaceutical formulations - F2α analogues in the glaucoma treatment.

Author: Asendrych-WicikKatarzyna, CiachTomasz, Markowicz-PiaseckaMagdalena, WalaszekKatarzyna, ZarczukJakub

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review discusses analytical methods for determining the content and related substances in PGF2α analogues used for glaucoma treatment. The instability of these analogues in aqueous solution and the phenomenon of isomerism are highlighted as important factors influencing the development of stability-indicating analytical methods.
Paper Details　
Original Abstract of the Article :
The ocular delivery route presents a number of challenges in terms of drug administration and bioavailability. The low bioavailability following topical ophthalmic administration shows that there is a clear need for in-depth research aimed at finding both more efficacious molecules and formulations ...See full text at original site
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引用元：
https://doi.org/10.1016/j.ejps.2022.106315

データ提供：米国国立医学図書館（NLM）

Trends in development and quality assessment of pharmaceutical formulations - F2α analogues in the glaucoma treatment

This study explores the evolving landscape of [緑内障] treatment, focusing on the development and quality assessment of pharmaceutical formulations. The authors discuss the challenges of ocular drug delivery and the need for targeted formulations that enhance bioavailability. They also highlight the importance of impurity profiling and the development of specific analytical methods to ensure the quality of F2α analogues used in glaucoma treatment.

A Desert Oasis of Innovation in Glaucoma Treatment

This study showcases the ongoing efforts to improve the treatment of glaucoma through advancements in pharmaceutical formulations. The authors highlight the challenges of ocular drug delivery and the need for innovations that enhance bioavailability and minimize side effects. This research serves as a testament to the dedication of scientists and pharmaceutical professionals in finding new solutions to combat this debilitating condition.

Navigating the Terrain of Glaucoma Treatment

Glaucoma treatment is like a desert journey, requiring careful navigation to achieve optimal outcomes. This study emphasizes the crucial role of pharmaceutical formulations in improving drug delivery and efficacy. The authors highlight the importance of quality assessment and analytical methods to ensure that medications are safe and effective, helping patients navigate the complexities of glaucoma treatment.

Dr.Camel's Conclusion

This study offers a comprehensive overview of the trends in development and quality assessment of pharmaceutical formulations used in glaucoma treatment. The authors underscore the importance of ongoing innovation to improve drug delivery and bioavailability, ultimately enhancing patient outcomes. This research is a testament to the dedication of scientists in finding solutions to combat this debilitating condition.
Date :
  1. Date Completed 2022-12-14
  2. Date Revised 2022-12-21
Further Info :

Pubmed ID

36367507

DOI: Digital Object Identifier

10.1016/j.ejps.2022.106315

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English

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