Paper Details

  1. Home
  2. Paper Details

The effect of rebamipide on non-steroidal anti-inflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study.

Author: ChoiYoon Jin, HaYou-Jung, KangEun Ha, KimHyun Soo, KimKi-Jeoung, KimNayoung, LeeDong Ho, LeeYun Jong, LiuFei, OhDong Jun, ParkYoung Soo, ShinCheol Min, YoonHyuk

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

This study examines the efficacy, safety, and gastrointestinal effects of rebamipide and proton pump inhibitors (PPIs) in patients requiring long-term non-steroidal anti-inflammatory drug (NSAID) use. NSAIDs are commonly prescribed for conditions like arthritis and heart disease but can lead to gastrointestinal problems such as bleeding and ulcers. The study aims to evaluate the benefits and risks associated with rebamipide and PPIs in mitigating these gastrointestinal complications.
Paper Details　
Original Abstract of the Article :
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly-used medications, and ailments such as arthritis or heart disease, require long-term use of these drugs, which can induce gastroenteropathy with bleeding and ulcers. This study investigated the associations between efficacy, safety, and gas...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9666262/

データ提供：米国国立医学図書館（NLM）

Rebamipide for NSAID-Induced Gastro-Enteropathy: A Pilot Study

The study of gastrointestinal health is a fascinating and complex field, and this research tackles a common challenge faced by individuals taking non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs are widely used for pain relief, but they can sometimes cause gastro-enteropathy, leading to bleeding and ulcers. The researchers investigated the effectiveness and safety of rebamipide, a medication used to protect the stomach lining, in patients requiring long-term NSAID use. The goal was to determine if rebamipide could mitigate the gastrointestinal side effects associated with NSAID use.

Rebamipide: A Potential Solution for NSAID-Induced Gastro-Enteropathy

The pilot study found that rebamipide may be effective in preventing gastrointestinal symptoms associated with long-term NSAID use. The researchers observed a positive association between rebamipide administration and a reduction in gastrointestinal symptoms, suggesting that this medication could offer valuable protection for individuals requiring long-term NSAID therapy. Further research is needed to confirm these findings and determine the optimal dosage and duration of rebamipide treatment.

Protecting Your Gut: Understanding NSAID Risks

If you are taking NSAIDs for an extended period, it's crucial to be aware of the potential risks of gastrointestinal complications. Talk to your healthcare provider about ways to mitigate these risks, such as taking rebamipide or other stomach-protective medications. Remember, taking care of your gut health is like ensuring the stability of a desert oasis. With the right measures, you can maintain a healthy balance and minimize any potential complications.

Dr. Camel's Conclusion

This study offers a glimmer of hope for individuals who rely on NSAIDs for pain relief. Rebamipide, like a protective shield against the harsh desert sun, may help to prevent the damaging effects of these medications on the stomach lining. However, it's essential to consult with your doctor to determine the best course of action for managing your pain and protecting your gut health.

Date :
  1. Date Completed 2022-11-16
  2. Date Revised 2022-11-29
Further Info :

Pubmed ID

36375487

DOI: Digital Object Identifier

PMC9666262

Related Literature

Article Analysis
・Side Effects of lansoprazole
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.