Addition of intravitreal carboplatin with melphalan for management of vitreous seeding in retinoblastoma.

Author: AminiAbdulrahim, BoujabadiLeila, GhassemiFariba, KhodabandehAlireza, MasoomianBabak, Riazi-EsfahaniHamid, SharifkashaniShervin, ShieldsCarol L, TaghizadehSara

Paper Details 
Original Abstract of the Article :
PURPOSE: To evaluate the efficacy and toxicity of intravitreal carboplatin plus melphalan for the treatment of vitreous seeds in eyes with retinoblastoma (RB). METHODS: This retrospective series at a tertiary referral center included 22 consecutive RB patients who had received intravitreal carbopla...See full text at original site
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引用元:
https://doi.org/10.1007/s00417-022-05903-3

データ提供:米国国立医学図書館(NLM)

Carboplatin Plus Melphalan: Combating Vitreous Seeding in Retinoblastoma

Retinoblastoma, a rare eye cancer that primarily affects children, can pose a significant threat to vision and overall health. This study investigates the efficacy and safety of intravitreal carboplatin combined with melphalan for the treatment of vitreous seeding, a common complication of retinoblastoma. Think of this research as a skilled surgeon wielding a precise scalpel to combat a formidable enemy. The researchers meticulously analyzed the outcomes of 22 patients who received this combination therapy, assessing its effectiveness in controlling vitreous seeds and minimizing potential side effects.

A Promising Treatment Strategy

The study suggests that carboplatin plus melphalan therapy may be an effective and well-tolerated treatment option for vitreous seeding in retinoblastoma. This approach offers a potential alternative to traditional treatments and holds promise for improving patient outcomes.

The Importance of Early Detection and Treatment

This research underscores the importance of early detection and prompt treatment for retinoblastoma. Just as a camel relies on its keen senses to navigate the desert landscape, healthcare providers must be vigilant in identifying and treating eye cancers to minimize the risk of complications like vitreous seeding.

Dr. Camel's Conclusion

This study offers a glimmer of hope for children diagnosed with retinoblastoma. Just as a desert oasis provides sustenance and relief, this novel treatment strategy may offer a vital lifeline for patients facing this challenging disease. The research encourages continued investigation into effective treatments for retinoblastoma, striving to improve patient outcomes and preserve vision for those affected by this rare cancer.
Date :
  1. Date Completed 2023-03-30
  2. Date Revised 2023-03-30
Further Info :

Pubmed ID

36401651

DOI: Digital Object Identifier

10.1007/s00417-022-05903-3

Related Literature

SNS
PICO Info
in preparation
Languages

English

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