Paper Details

  1. Home
  2. Paper Details

Ocular Side Effects of Bisphosphonates: A Review of Literature.

Author: ChartrandNicholas A, HandlonJaiden J, HoopesPhillip C, LauChap-Kay, MoshirfarMajid, ParsonsMark T, RonquilloYasmyne C

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This review examined the ocular complications associated with bisphosphonates. It was found that second- and third-generation amino bisphosphonates are associated with ocular inflammation, including uveitis, episcleritis, and scleritis. Symptoms often resolve after discontinuation of the drug and anti-inflammatory treatment. The mechanism of bisphosphonate-induced ocular inflammation may involve activation of specific immune cells.
Paper Details　
Original Abstract of the Article :
In rare cases, bisphosphonates are well established to cause ocular inflammation, presenting as uveitis, episcleritis, scleritis, orbital inflammation, and/or conjunctivitis. Some reports of bisphosphonate-associated neuro-ophthalmic complications also exist. We identified 101 reports in the literat...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1089/jop.2022.0094

データ提供：米国国立医学図書館（NLM）

Bisphosphonates: A Double-Edged Sword in Bone Health

Bisphosphonates are a class of medications frequently used to treat osteoporosis and certain cancers. While they are generally effective, they can also cause some adverse side effects. This research delves into the potential for bisphosphonates to cause ocular inflammation, a condition that can significantly impact vision. The researchers reviewed the available literature to assess the prevalence, characteristics, and possible mechanisms of bisphosphonate-induced ocular inflammation.

Navigating the Side Effects of Bisphosphonates

The research highlights the potential for bisphosphonates to cause ocular inflammation, a condition that can be quite uncomfortable and affect vision. This research emphasizes the need for careful monitoring and prompt management of this side effect.

Protecting Your Eyes: A Reminder about Medication Safety

This research underscores the importance of being aware of the potential side effects of medications, even those commonly used for bone health. If you experience any changes in your vision, especially if you are taking bisphosphonates, it is important to consult your doctor promptly.

Dr.Camel's Conclusion

This review of the literature sheds light on the potential for bisphosphonates to cause ocular inflammation. While this side effect is rare, it is important to be aware of the possibility and to seek medical attention if you experience any changes in your vision.

Date :
  1. Date Completed 2023-01-30
  2. Date Revised 2023-02-10
Further Info :

Pubmed ID

36409537

DOI: Digital Object Identifier

10.1089/jop.2022.0094

Related Literature

Article Analysis
・Side Effects of risedronate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.