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Preliminary verification of the anti-hypoxia mechanism of Gentiana straminea maxim based on UPLC-triple TOF MS/MS and network pharmacology.

Author: GaoXiao Min, GeMing Juan, JiangYi, KongXiu Mei, LiJie, SongDan, WuXiao Jun, XuJiao Jiao, ZhangXiao Ying, ZhaoQin

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This article explores the anti-hypoxia effects of Gentiana straminea Maxim (G.s Maxim), a traditional Tibetan medicine. The authors found that the ethyl acetate extract of G.s Maxim mediated resistance to hypoxia but the primary anti-hypoxia components and mechanisms of action remain unclear.
Paper Details　
Original Abstract of the Article :
Anoxia is characterized by changes in the morphology, metabolism, and function of tissues and organs due to insufficient oxygen supply or oxygen dysfunction. Gentiana straminea Maxim (G.s Maxim) is a traditional Tibetan medicine. Our previous work found that G.s Maxim mediates resistance to hypoxia,...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700950/

データ提供：米国国立医学図書館（NLM）

Gentiana straminea Maxim: A Potential Anti-Hypoxia Remedy

The human body is a complex system that relies on oxygen for survival. This research investigates the potential of Gentiana straminea Maxim (G.s Maxim), a traditional Tibetan medicine, to combat the effects of hypoxia, a condition characterized by insufficient oxygen supply.

The study used UPLC-triple TOF MS/MS and network pharmacology to identify potential anti-hypoxia components and mechanisms of action in G.s Maxim. The research suggests that G.s Maxim, particularly the ethyl acetate extract, may offer promising therapeutic benefits for combating hypoxia.

Unlocking the Power of Traditional Medicine

This study highlights the value of exploring traditional medicine for potential therapeutic applications. The research suggests that G.s Maxim could offer a natural approach to addressing the challenges of hypoxia.

The Importance of Oxygen

Imagine the desert as a vast and arid environment, where the lack of water is a constant threat. Just as water is essential for survival in the desert, oxygen is crucial for the human body. This study emphasizes the importance of understanding and addressing conditions that affect oxygen supply.

Dr.Camel's Conclusion

This research is like a journey across a vast desert, uncovering the hidden treasures of traditional medicine. The study suggests that G.s Maxim could be a valuable tool for combating hypoxia, a condition that can be as challenging to navigate as a vast and unforgiving desert. It's a reminder that the wisdom of traditional medicine holds valuable insights for modern healthcare.

Date :
  1. Date Completed 2022-11-29
  2. Date Revised 2022-12-13
Further Info :

Pubmed ID

36434600

DOI: Digital Object Identifier

PMC9700950

SNS
PICO Info
in preparation
Languages

English

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