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Terminalia bellirica ethanol extract ameliorates nonalcoholic fatty liver disease in mice by amending the intestinal microbiota and faecal metabolites.
Author: GongPuyang, GuJian, HanCairong, LiuJingxian, LuoXiaomin, QiJin, TanRui, ZhangBoyu, ZhangLe
Original Abstract of the Article :
ETHNOPHARMACOLOGICAL RELEVANCE: Terminalia bellirica (Gaertn.) Roxb. (TB) is a traditional Tibetan medicine used to treat hepatobiliary diseases. However, modern pharmacological evidence of the activities and potential mechanisms of TB against nonalcoholic fatty liver disease (NAFLD) are still unkno...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.jep.2022.116082
データ提供:米国国立医学図書館(NLM)
Terminalia bellirica: A Potential Natural Remedy for Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) is a growing health concern, affecting millions worldwide. This study, published in the journal Journal of Ethnopharmacology, explores the potential of Terminalia bellirica (TB), a traditional Tibetan medicine used to treat liver ailments, as a natural remedy for NAFLD. The researchers investigated the effects of an ethanol extract of TB (ETB) on mice with diet-induced NAFLD. They examined the impact of ETB on liver function, gut microbiota composition, and fecal metabolites.
Terminalia bellirica: A Promising Natural Treatment
The study found that ETB significantly improved liver function and reduced liver damage in mice with NAFLD. The researchers also observed that ETB altered the composition of the gut microbiota, increasing the abundance of beneficial bacteria and reducing the levels of harmful bacteria. Furthermore, ETB restored the balance of key metabolites involved in liver health, suggesting its potential to modulate the gut microbiome and its impact on liver function.
A Holistic Approach to NAFLD: Mind and Gut
This study highlights the potential of TB as a natural remedy for NAFLD. It emphasizes the importance of a holistic approach to liver health, taking into account the interplay between diet, lifestyle, and the gut microbiome. Just as a desert ecosystem thrives on a delicate balance of flora and fauna, our bodies rely on a healthy gut microbiome for overall well-being, including liver health.
Dr. Camel's Conclusion
This study offers an intriguing glimpse into the potential of traditional medicine to address modern health challenges. The positive effects of Terminalia bellirica on NAFLD suggest that nature holds a wealth of untapped solutions for various health problems. Just as a desert traveler relies on the knowledge of local guides, we should explore and embrace the wisdom of traditional healing systems.
Date :
- Date Completed 2023-01-24
- Date Revised 2023-02-01
Further Info :
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