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Pharmacological treatment of alcohol use disorder in patients with psychotic disorders: A systematic review.

Author: AnhøjSimon, HøjlundMikkel, MellentinAngelina Isabella, NielsenAnette Søgaard, NielsenDorthe Grüner, RosenstandNiels Jørgen, SkøtLotte

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This systematic review examined the effectiveness and safety of pharmacological treatments for alcohol use disorder (AUD) in patients with psychotic disorders (PD). The review found tentative support for the use of naltrexone and disulfiram, while other agents like acamprosate and nalmefene showed mixed results. The review emphasized the need for further research to explore the safety and effectiveness of polypharmacy for AUD in this population.
Paper Details　
Original Abstract of the Article :
Patients with psychotic disorders (PD) often have comorbid alcohol use dis- order (AUD), which is typically treated pharmacologically. Up till now, no systematic review has ex- amined the effectiveness and safety of AUD treatment in PD patients. </P> <P> Objectives: This study aimed to systematicall...See full text at original site
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引用元：
https://doi.org/10.2174/1570159X21666221229160300

データ提供：米国国立医学図書館（NLM）

Pharmacological Treatment of Alcohol Use Disorder in Patients with Psychotic Disorders

The study aims to provide an overview of the effectiveness of pharmacotherapy for alcohol use disorder (AUD) in individuals with comorbid psychotic disorders (PD). The researchers are interested in learning about the efficacy and safety of various medications commonly used to treat AUD and how these drugs may impact drinking outcomes and potential side effects.

Potential Benefits and Risks of Pharmacotherapy for AUD in PD Patients

The researchers found limited evidence supporting the effectiveness of specific pharmacological treatments for AUD in patients with PD. The findings suggest that naltrexone and disulfiram might be helpful in reducing alcohol intake, although further research is needed to confirm these results. They also emphasized the importance of monitoring patients closely for potential side effects and considering the potential risks associated with polypharmacy.

Navigating the Complexities of Comorbid AUD and PD

This study sheds light on the complexities of treating AUD in patients with PD. It's like navigating a desert with multiple pathways – each patient presents a unique set of challenges, and finding the right treatment approach requires careful consideration of their individual needs and the potential benefits and risks of different medications.

Dr. Camel's Conclusion

This study is like a desert oasis, offering a much-needed respite for those struggling with comorbid AUD and PD. It reveals the importance of careful consideration and individualized approaches to treatment, ensuring that patients receive the best possible care and support.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-12-30
Further Info :

Pubmed ID

36582063

DOI: Digital Object Identifier

10.2174/1570159X21666221229160300

Related Literature

Article Analysis
・Effective treatment of psychotic disorders
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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