Cost-Effectiveness Analysis of Macitentan in Comparison With Bosentan in the Treatment of Pulmonary Arterial Hypertension in Iran.

Author: EkhlasiMahna, MajdZahra Karimi, PeiravianFarzad, SheikhiShiva, YousefiNazila

Paper Details 
Original Abstract of the Article :
Pulmonary arterial hypertension (PAH) is a chronic and progressive disease that, if left untreated, shortens the life expectancy of patients. Endothelin receptor antagonists, such as macitentan and bosentan, play an essential role in improving the patient's symptoms, quality of life, and life expect...See full text at original site
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引用元:
https://doi.org/10.1016/j.vhri.2022.10.001

データ提供:米国国立医学図書館(NLM)

Cost-Effectiveness Analysis of Macitentan vs. Bosentan in PAH

Pulmonary arterial hypertension (PAH) is a chronic and progressive disease that can significantly impact patients' lives. This study focuses on the cost-effectiveness of two endothelin receptor antagonists, macitentan and bosentan, used to treat PAH. Researchers analyzed the cost-utility of macitentan compared to bosentan from the perspective of the Iranian health system.

Macitentan Offers a Potential Cost-Effective Option

The study concludes that macitentan may be a more cost-effective treatment option for PAH compared to bosentan in the Iranian healthcare system. This finding has significant implications for healthcare resource allocation and treatment decisions for PAH patients. The authors used a robust cost-utility analysis, taking into account both the effectiveness of the treatments and their associated costs, which is crucial for making informed decisions regarding healthcare resource allocation.

A Camel's Perspective on PAH Treatment

Imagine a camel traversing a harsh desert landscape, facing challenges like dehydration and scorching sun. PAH patients face similar challenges as their hearts struggle to pump blood effectively through constricted blood vessels. This study provides valuable information for healthcare providers seeking the most effective and cost-effective treatment options for PAH, aiding them in providing the best possible care for their patients.

Dr.Camel's Conclusion

This study provides evidence that macitentan may be a cost-effective alternative to bosentan for PAH patients in Iran. This finding can inform healthcare decision-making and contribute to more efficient resource allocation for the management of PAH.

Date :
  1. Date Completed 2023-03-07
  2. Date Revised 2023-03-07
Further Info :

Pubmed ID

36599206

DOI: Digital Object Identifier

10.1016/j.vhri.2022.10.001

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