Paper Details 
Original Abstract of the Article :
With rapid advances in immuno-oncology, immune checkpoint inhibitors (ICIs) are increasingly used for a broad array of malignancies. This has led to a novel spectrum of adverse effects including ICI-related myositis, a potentially life-threatening neuromuscular complication that must be diagnosed an...See full text at original site
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引用元:
https://doi.org/10.55563/clinexprheumatol/q7mdjs

データ提供:米国国立医学図書館(NLM)

Navigating the Complexities of Immune Checkpoint Inhibitor-Related Myositis

The field of immuno-oncology has witnessed significant advancements, with immune checkpoint inhibitors (ICIs) revolutionizing cancer treatment. While ICIs offer tremendous promise, they can also lead to a range of adverse effects, including ICI-related myositis, a potentially life-threatening neuromuscular complication. This study delves into the pathophysiology, epidemiology, clinical features, workup, and management of ICI-related myositis, highlighting the critical need for timely diagnosis and treatment.

The study emphasizes the challenges posed by the rarity of ICI-related myositis and the lack of evidence-based guidelines. The researchers call for a collaborative effort to synthesize existing knowledge and advance research in this area to improve patient care.

ICI-Related Myositis: A Complex and Emerging Challenge

This study sheds light on the complexities of ICI-related myositis, a potentially serious complication of cancer immunotherapy. The study highlights the need for heightened awareness of this condition among healthcare professionals and for the development of evidence-based guidelines to guide diagnosis and treatment.

Understanding the Balancing Act of Cancer Treatment

Just as a camel navigating a desert must find a balance between hydration and conserving energy, cancer treatment requires a delicate balance between achieving therapeutic efficacy and managing potential adverse effects. This study highlights the importance of understanding the potential complications associated with new treatments and developing strategies to address them.

Dr.Camel's Conclusion

This comprehensive review of ICI-related myositis provides valuable insights into the pathophysiology, clinical features, and management of this potentially life-threatening complication of cancer immunotherapy. The study underscores the need for continued research and development of evidence-based guidelines to ensure optimal patient care in this emerging field.

Date :
  1. Date Completed 2023-03-03
  2. Date Revised 2023-03-03
Further Info :

Pubmed ID

36622122

DOI: Digital Object Identifier

10.55563/clinexprheumatol/q7mdjs

Related Literature

SNS
PICO Info
in preparation
Languages

English

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