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The Role of Glucocorticoids in Breast Cancer Therapy.

Author: Jacobo-HerreraNadia J, MaldonadoVilma, Melendez-ZajglaJorge, Mendoza-AlmanzaGretel, Mitre-AguilarIrma B, Moreno-MitreDaniel, Ramirez-GonzalezVictoria

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Glucocorticoids (GCs) play a significant role in breast cancer, both as a marker of poor prognosis and a therapeutic target for triple-negative breast cancer (TNBC). The review summarizes the literature on GCs in breast cancer, highlighting the clinical utility of dexamethasone as an antiemetic and the ongoing efforts to develop better GR antagonists with fewer side effects.
Paper Details　
Original Abstract of the Article :
Glucocorticoids (GCs) are anti-inflammatory and immunosuppressive steroid molecules secreted by the adrenal gland and regulated by the hypothalamic-pituitary-adrenal (HPA) axis. GCs present a circadian release pattern under normal conditions; they increase their release under stress conditions. Thei...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9858160/

データ提供：米国国立医学図書館（NLM）

The Role of Glucocorticoids in the Desert of Breast Cancer Treatment

The battle against [breast cancer] is a complex and challenging one, and researchers are constantly seeking new and innovative therapies. This research delves into the potential role of [glucocorticoids] in treating breast cancer, exploring their mechanisms of action and potential therapeutic benefits. By understanding the complex interactions of glucocorticoids with breast cancer cells, researchers aim to develop more targeted and effective treatment strategies.

Glucocorticoids: A New Oasis in the Desert of Breast Cancer Treatment?

This study investigates the potential of [glucocorticoids] as a therapeutic agent for [breast cancer]. The findings suggest that these agents may play a role in treating triple-negative breast cancer, potentially offering a new avenue for targeting this aggressive subtype of the disease. This research highlights the importance of understanding the complex interactions of glucocorticoids with breast cancer cells to develop more effective and personalized treatment strategies.

The Future of Breast Cancer Treatment: Navigating the Sands of Glucocorticoid Therapy

This research explores the potential role of [glucocorticoids] in the complex landscape of [breast cancer] treatment. The findings suggest that these agents may offer a promising new avenue for targeting triple-negative breast cancer, potentially leading to more effective and personalized treatment strategies. This research underscores the importance of continued research and development to explore the potential benefits and risks of glucocorticoid therapy in breast cancer.

Dr.Camel's Conclusion

This study sheds light on the potential of glucocorticoids as a therapeutic agent for breast cancer, particularly for the triple-negative subtype. While further research is needed to fully understand their role in breast cancer treatment, these findings suggest a promising new avenue for targeting this challenging disease.

Date :
  1. Date Completed 2023-01-24
  2. Date Revised 2023-11-22
Further Info :

Pubmed ID

36661673

DOI: Digital Object Identifier

PMC9858160

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Languages

English

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