Paper Details 
Original Abstract of the Article :
Elexacaftor/tezacaftor/ivacaftor (E/T/I) therapy has resulted in substantial improvements in health status for many with cystic fibrosis. Monitoring of liver tests is recommended due to observed rises in transaminases in trials and cases of hepatotoxicity. Comprehensive data in large populations of ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1016/j.jcf.2023.01.007

データ提供:米国国立医学図書館(NLM)

Elexacaftor/Tezacaftor/Ivacaftor: Monitoring Liver Health in Cystic Fibrosis Patients

Elexacaftor/tezacaftor/ivacaftor (E/T/I) therapy has shown significant improvements in the health of many individuals with cystic fibrosis. However, monitoring liver function is crucial due to potential liver toxicity. This study examines the long-term effects of E/T/I on liver tests in a large group of cystic fibrosis patients at a single center.

E/T/I's Impact on Liver Function: A Comprehensive Assessment

The study found that while E/T/I therapy has proven beneficial for cystic fibrosis patients, it is important to closely monitor liver function due to potential risks of elevated transaminases and hepatotoxicity. The research emphasizes the need for continued monitoring of liver health in these patients.

Cystic Fibrosis Management: A Balancing Act

This research provides valuable information for managing cystic fibrosis patients on E/T/I therapy. Close monitoring of liver function is essential to ensure optimal patient care and mitigate any potential complications.

Dr. Camel's Conclusion

Imagine E/T/I therapy as a refreshing oasis in the arid landscape of cystic fibrosis. While this therapy offers significant benefits, it's important to keep a watchful eye on liver health, like a camel guarding its water source. This study reminds us that vigilance is crucial in managing complex conditions like cystic fibrosis.

Date :
  1. Date Completed 2023-05-01
  2. Date Revised 2023-06-03
Further Info :

Pubmed ID

36669962

DOI: Digital Object Identifier

10.1016/j.jcf.2023.01.007

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.