Baloxavir safety and clinical and virologic outcomes in influenza virus-infected pediatric patients by age group: age-based pooled analysis of two pediatric studies conducted in Japan.

Author: FukaoKeita, HirotsuNobuo, KojimaSatoshi, PiedraPedro A, SakaguchiHiroki, TsuchiyaKenji, UeharaTakeki

Paper Details 
Original Abstract of the Article :
BACKGROUND: Anti-influenza treatment is important for children and is recommended in many countries. This study assessed safety, clinical, and virologic outcomes of baloxavir marboxil (baloxavir) treatment in children based on age and influenza virus type/subtype. METHODS: This was a post hoc poole...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9860230/

データ提供:米国国立医学図書館(NLM)

Baloxavir Marboxil: A Safe and Effective Anti-Influenza Treatment for Children

The flu season can be a turbulent and unpredictable journey, particularly for children. This study examines the safety and efficacy of baloxavir marboxil (baloxavir) in treating influenza virus-infected pediatric patients in Japan. It's like searching for a reliable and safe treatment in a desert of viruses and potential complications.

Baloxavir: A Safe and Effective Treatment for Children

The study found that baloxavir was safe and effective in treating children with influenza, across all age groups and influenza virus types. The most common adverse events were mild to moderate, and the treatment led to a significant reduction in symptoms and viral shedding. This is like finding a safe and effective antidote in the desert, providing relief and protection from the harmful effects of a viral infection.

Considerations for Young Children

While baloxavir appears to be safe and effective, the study found that young children (<6 years) were more likely to experience fever recurrence and transient virus titer increases. This highlights the need for careful monitoring of young children treated with baloxavir, similar to navigating a sandstorm with extra caution.

Dr. Camel's Conclusion

This study provides valuable information about the use of baloxavir for children with influenza. It offers hope for families seeking effective treatment for this common and potentially serious illness. The findings are a beacon of light in the desert of influenza infections, guiding us towards safer and more effective treatment options for children.

Date :
  1. Date Completed 2023-01-26
  2. Date Revised 2023-11-16
Further Info :

Pubmed ID

36681802

DOI: Digital Object Identifier

PMC9860230

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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