The effects of oral ferrous bisglycinate supplementation on hemoglobin and ferritin concentrations in adults and children: a systematic review and meta-analysis of randomized controlled trials.

Author: BoneJeffrey N, CherianArlin M, FischerJordie A J, KarakochukCrystal D

Paper Details 
Original Abstract of the Article :
Iron deficiency and anemia have serious consequences, especially for children and pregnant women. Iron salts are commonly provided as oral supplements to prevent and treat iron deficiency, despite poor bioavailability and frequently reported adverse side effects. Ferrous bisglycinate is a novel amin...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10331582/

データ提供:米国国立医学図書館(NLM)

Iron Supplementation: A Matter of Absorption and Side Effects

Iron deficiency anemia is a common health concern, especially among children and pregnant women. This research focuses on the effectiveness and safety of ferrous bisglycinate, a novel form of iron supplementation, compared to traditional iron salts. The authors conducted a systematic review and meta-analysis of randomized controlled trials to evaluate the impact of ferrous bisglycinate on hemoglobin and ferritin levels, key indicators of iron status. Their findings suggest that ferrous bisglycinate may offer advantages in terms of bioavailability and gastrointestinal tolerability compared to traditional iron salts.

Ferrous Bisglycinate: A More Bioavailable Option

The meta-analysis revealed that ferrous bisglycinate significantly increased hemoglobin and ferritin levels compared to placebo, demonstrating its efficacy in improving iron status. Importantly, the study also found that ferrous bisglycinate was associated with fewer gastrointestinal side effects compared to traditional iron salts. These findings suggest that ferrous bisglycinate may be a more effective and tolerable option for iron supplementation, especially for individuals who experience gastrointestinal distress with traditional iron salts.

Implications for Iron Supplementation Practices

This study provides strong evidence for the potential benefits of ferrous bisglycinate as an iron supplement. The findings suggest that ferrous bisglycinate could be a preferred option for individuals requiring iron supplementation, particularly those who experience gastrointestinal side effects with traditional iron salts. However, further research is needed to explore its long-term safety and efficacy in different patient populations.

Dr.Camel's Conclusion

Just as a camel relies on a steady supply of water to traverse the desert, our bodies need iron to function properly. This research highlights the potential of ferrous bisglycinate as a more bioavailable and tolerable form of iron supplementation compared to traditional iron salts. This study offers a promising alternative for individuals struggling with iron deficiency, paving the way for improved iron supplementation practices and better health outcomes.

Date :
  1. Date Completed 2023-07-21
  2. Date Revised 2023-07-21
Further Info :

Pubmed ID

36728680

DOI: Digital Object Identifier

PMC10331582

Related Literature

SNS
PICO Info
in preparation
Languages

English

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