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Vitamin D for the management of asthma.

Author: GriffithsChris J, JolliffeDavid, MartineauAdrian R, SheikhAziz, WilliamsonAnne

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

An updated Cochrane review of 20 studies found no evidence to support a role for vitamin D supplementation or its hydroxylated metabolites in reducing the risk of asthma exacerbations or improving asthma control. The review included 15 trials involving children and 5 trials involving adults. Further research is warranted in patients with severe asthma and those with baseline 25-hydroxyvitamin D (25(OH)D) concentrations less than 25 nmol/L.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Since the previous Cochrane Review on this topic in 2016, debate has continued surrounding a potential role for vitamin D in reducing risk of asthma exacerbation and improving asthma control. We therefore conducted an updated meta-analysis to include data from new trials completed since ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899558/

データ提供：米国国立医学図書館（NLM）

Vitamin D: A Potential Solution for Asthma Exacerbations?

This study delves into the intriguing world of vitamin D and its potential role in asthma management, exploring whether vitamin D supplementation can reduce the risk of asthma exacerbations and improve asthma control. The researchers conducted a comprehensive meta-analysis of 20 randomized controlled trials, evaluating the effects of vitamin D administration on various asthma outcomes, including exacerbation rates, symptom control, and lung function.

Vitamin D: A Mirage in the Desert of Asthma Research

The study's findings, however, provide no evidence to support a role for vitamin D supplementation in reducing the risk of asthma exacerbations or improving asthma control. This conclusion contradicts the findings of previous research suggesting a potential benefit of vitamin D in asthma. The researchers acknowledge the need for further research, particularly in individuals with severe asthma and those with profound vitamin D deficiency, to fully understand the potential role of vitamin D in asthma management.

Navigating the Complexities of Asthma Management: A Multifaceted Approach

This study highlights the need for a multidisciplinary approach to asthma management, considering a wide range of factors that may influence asthma severity and response to treatment. While vitamin D supplementation did not show a significant benefit in this meta-analysis, other interventions, such as medication adherence, environmental control, and lifestyle modifications, may play a crucial role in improving asthma control and reducing exacerbation risk.

Dr. Camel's Conclusion

Vitamin D, often touted as a miracle cure for various health conditions, appears to be a mirage in the desert of asthma research. This study, like a dry and dusty wind, blows away the hope that vitamin D supplementation alone can significantly improve asthma control. However, the journey of scientific discovery is a long and winding one. Further research is needed to explore the complex interplay of vitamin D, asthma, and other factors that may influence asthma severity and response to treatment.

Date :
  1. Date Completed 2023-02-07
  2. Date Revised 2023-08-01
Further Info :

Pubmed ID

36744416

DOI: Digital Object Identifier

PMC9899558

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SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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