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Investigation of the antimicrobial effect of anodic iontophoresis on Gram-positive and Gram-negative bacteria for skin infections treatment.

Author: AiresCarolina Patrícia, Araújo MartinsYugo, Dos Santos RéAna Carolina, Facco DalmolinLuciana, Fonseca Vianna LopezRenata, Gerotto ViolaSofia, Villarruel MuñozJanette Betzabeth

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Iontophoresis, a non-invasive electrical therapy, has shown antimicrobial effects on bacteria. In this study, iontophoresis showed a greater effect on Gram-negative bacteria, causing up to 98% death and significant morphological changes, compared to Gram-positive bacteria. This suggests that iontophoresis can be a valuable tool for wound healing by controlling Gram-negative bacterial growth.
Paper Details　
Original Abstract of the Article :
Iontophoresis, a non-invasive application of a constant low-intensity electric current, is a promising strategy to accelerate wound healing. Although its mechanisms are not yet fully elucidated, part of its action seems related to inhibiting bacteria growth. This work aimed to investigate the antimi...See full text at original site
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引用元：
https://doi.org/10.1016/j.bioelechem.2023.108374

データ提供：米国国立医学図書館（NLM）

Anodic Iontophoresis: A New Weapon in the Fight Against Skin Infections

Skin infections are a common ailment, often requiring timely and effective treatment. This study explores the potential of anodic iontophoresis, a non-invasive technique that uses a low-intensity electric current, to combat bacterial growth in skin infections. The authors investigated the antimicrobial effects of anodic iontophoresis on both Gram-positive and Gram-negative bacteria, revealing promising results.

Anodic Iontophoresis: A Targeted Approach to Combating Bacterial Growth

The study demonstrated that anodic iontophoresis exhibited antimicrobial effects against Gram-negative bacteria, causing significant morphological changes and bacterial death. While the effect on Gram-positive bacteria was less pronounced, the findings suggest that anodic iontophoresis could be a valuable tool for controlling bacterial proliferation in wounds.

A New Oasis in the Desert of Skin Infections: Anodic Iontophoresis

This research opens new avenues for treating skin infections. Anodic iontophoresis offers a non-invasive and potentially effective approach to combating bacterial growth, potentially reducing the need for antibiotics and their associated side effects.

Dr.Camel's Conclusion

Anodic iontophoresis, like a camel using its powerful legs to navigate the desert, may offer a novel and effective way to combat skin infections. This research is a promising step towards a future where we have more tools to fight bacterial growth and promote wound healing.

Date :
  1. Date Completed 2023-03-28
  2. Date Revised 2023-03-28
Further Info :

Pubmed ID

36750011

DOI: Digital Object Identifier

10.1016/j.bioelechem.2023.108374

Related Literature

Article Analysis
・Effective treatment of skin infections
SNS
PICO Info
in preparation
Languages

English

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