Safety of levofloxacin as an antibiotic prophylaxis in the induction phase of children newly diagnosed with acute lymphoblastic leukemia: an interim analysis of a randomized, open-label trial in Brazil.

Author: CarlesseFabianne Altruda de Moraes Costa, DaudtLiane Esteves, DufrayerMauro Cesar, MenesesClarice Franco, MichalowskiMariana Bohns, MonteiroYasmine Massaro Carneiro, MottaFabrizio, RechenmacherCiliana

Paper Details 
Original Abstract of the Article :
BACKGROUND: Despite high cure rates, treatment-related mortality in children with acute lymphoblastic leukemia (ALL) remains significant. About 4% of patients die during remission induction therapy and approximately two-thirds of treatment-related deaths are due to infectious complications. METHODS...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9978458/

データ提供:米国国立医学図書館(NLM)

Levofloxacin: A Safety Check in the Desert of Childhood Leukemia

Childhood leukemia is a serious condition that affects the blood and bone marrow. It's like a sandstorm that disrupts the body's normal function, affecting the ability to fight infection. This study looks at the safety of using levofloxacin, an antibiotic, as a preventive measure during treatment for childhood leukemia.

Protecting Against Infection: Navigating the Desert

This study investigated the safety of using levofloxacin in children undergoing treatment for acute lymphoblastic leukemia (ALL). It's like finding a way to protect ourselves from the dangers of the desert, creating a safe space to heal. The researchers found that levofloxacin was well-tolerated and did not increase the risk of serious side effects, like antibiotic-resistant infections, in these patients. It's like finding a safe passage through a treacherous landscape.

A Promising Finding

This study suggests that levofloxacin could be a valuable tool in protecting children with ALL from infections during treatment. It's like finding a new oasis in the desert, offering a source of strength and resilience. This research is a positive development in the fight against this challenging disease, providing hope for a better future for these children.

Dr.Camel's Conclusion

This study reminds us that even in the most challenging of circumstances, there's always hope for finding solutions. It's like discovering a hidden spring in the desert, a source of life and renewal. This research is a testament to the dedication of healthcare professionals who are committed to finding ways to improve the health and well-being of children with leukemia.
Date :
  1. Date Completed 2023-03-28
  2. Date Revised 2023-03-28
Further Info :

Pubmed ID

36750202

DOI: Digital Object Identifier

PMC9978458

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.