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Cabozantinib, Vandetanib, Pralsetinib and Selpercatinib as Treatment for Progressed Medullary Thyroid Cancer with a Main Focus on Hypertension as Adverse Effect.
Author: GrimmDaniela, Højer WangLinnea, InfangerManfred, KreisslMichael C, WehlandMarkus, WisePetra M
Original Abstract of the Article :
This manuscript investigates cabozantinib, vandetanib, pralsetinib, and selpercatinib, four tyrosine kinase inhibitors (TKIs), which are used to treat advanced and/or metastatic medullary thyroid cancer (MTC). Data on efficacy and safety are presented with the main focus on treatment-related hyperte...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917177/
データ提供:米国国立医学図書館(NLM)
Battling Thyroid Cancer: A New Generation of Drugs
Medullary thyroid cancer (MTC), a type of thyroid cancer, can be challenging to treat. This manuscript explores the use of four tyrosine kinase inhibitors (TKIs) - cabozantinib, vandetanib, pralsetinib, and selpercatinib - for treating advanced or metastatic MTC. The authors discuss the efficacy and safety of these drugs, with a particular focus on a common side effect: hypertension. Their findings suggest that while these drugs can be effective in treating MTC, careful monitoring for hypertension is crucial.
TKIs: A Double-Edged Sword in Thyroid Cancer Treatment
This manuscript highlights the potential of TKIs for treating MTC, but also underscores the importance of managing their side effects, particularly hypertension. The authors acknowledge that while these drugs can be effective in treating MTC, careful monitoring and management of hypertension are necessary to ensure patient safety and optimize treatment outcomes. Further research is needed to explore alternative treatment strategies that minimize the risk of hypertension.
Managing Thyroid Health: A Collaborative Approach
The thyroid gland, like a vital oasis in the desert of our bodies, plays a crucial role in regulating metabolism. This manuscript underscores the importance of managing thyroid health, including monitoring for potential side effects of medications. It's a reminder that maintaining overall health, including a balanced diet, regular exercise, and stress management, can contribute to healthy thyroid function and well-being.
Dr.Camel's Conclusion
The desert of cancer treatment can be a challenging landscape, with its own unique obstacles and opportunities. This manuscript offers a glimpse into the potential of TKIs for treating MTC, but also highlights the need for careful monitoring and management of side effects. It's a reminder that even in the face of adversity, there is hope for a healthier future, as long as we approach treatment with a collaborative and informed mindset.
Date :
- Date Completed 2023-02-14
- Date Revised 2023-02-14
Further Info :
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