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Evaluation of contemporary olanzapine- and netupitant/palonosetron-containing antiemetic regimens for chemotherapy-induced nausea and vomiting.

Author: ChanV T C, KwokC C H, LauT K H, LiL, MoF K F, SuenJ J S, YeoW, YipC Ch

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
CommentA short article/note that provides an opinion/perspective/interpretation on a published paper/topic.

Overview

This study compared the effectiveness of olanzapine-based and netupitant/palonosetron (NEPA)-based antiemetic regimens in controlling chemotherapy-induced nausea and vomiting (CINV) during chemotherapy. The NEPA-based regimens showed similar efficacy to olanzapine-based regimens in controlling CINV, suggesting that NEPA may be a viable alternative for patients.
Paper Details　
Original Abstract of the Article :
This post-hoc analysis retrospectively assessed data from two recent studies of antiemetic regimens for chemotherapy-induced nausea and vomiting (CINV). The primary objective was to compare olanzapine-based versus netupitant/palonosetron (NEPA)-based regimens in terms of controlling CINV during cycl...See full text at original site
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引用元：
https://doi.org/10.12809/hkmj209182

データ提供：米国国立医学図書館（NLM）

Olanzapine and Netupitant/Palonosetron: Comparing Antiemetic Regimens for Chemotherapy-Induced Nausea and Vomiting

Chemotherapy is a vital treatment modality for cancer, but it can be associated with significant side effects, including nausea and vomiting. This study compares the effectiveness of olanzapine-based versus netupitant/palonosetron (NEPA)-based antiemetic regimens for chemotherapy-induced nausea and vomiting (CINV). The authors conducted a post-hoc analysis of data from two recent studies, assessing the efficacy of these regimens in controlling CINV during doxorubicin/cyclophosphamide (AC) chemotherapy. The results showed that both olanzapine-based and NEPA-based regimens were effective in controlling CINV, with no significant differences in terms of emesis outcomes or quality of life. The study provides valuable insights into the effectiveness of these antiemetic regimens for managing CINV.

Olanzapine and NEPA: Effective Antiemetics for Chemotherapy-Induced Nausea and Vomiting

The study demonstrates the effectiveness of both olanzapine-based and NEPA-based antiemetic regimens in controlling CINV. These regimens offer valuable tools for improving the patient experience and quality of life during chemotherapy treatment.

Olanzapine and NEPA: Optimizing Chemotherapy Treatment

This research highlights the importance of effective antiemetic strategies in managing the side effects of chemotherapy. The findings provide healthcare providers with valuable insights into the effectiveness of olanzapine-based and NEPA-based regimens, enabling them to optimize treatment plans for patients undergoing chemotherapy.

Dr.Camel's Conclusion

This study provides valuable insights into the effectiveness of olanzapine-based and NEPA-based antiemetic regimens for managing CINV. The findings underscore the importance of effective antiemetic strategies in optimizing chemotherapy treatment for patients.

Date :
  1. Date Completed 2023-02-24
  2. Date Revised 2023-06-06
Further Info :

Pubmed ID

36810240

DOI: Digital Object Identifier

10.12809/hkmj209182

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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