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Influence of Flavonoid-Rich Fraction of <i>Monodora tenuifolia</i> Seed Extract on Blood Biochemical Parameters in Streptozotocin-Induced Diabetes Mellitus in Male Wistar Rats.

Author: AyelesoAdemola, MorakinyoAdetoun, NtwasaMonde, NzekweSamuel, OguntibejuOluwafemi, OyedapoOluboade

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study evaluated the effects of a flavonoid-rich fraction of *Monodora tenuifolia* seed extract (FFMTSE) on blood parameters in diabetic rats. FFMTSE was found to significantly improve the lipid profile, reduce kidney function markers (urea and creatinine), and decrease cardiac enzyme activities in diabetic rats. These results suggest that FFMTSE might be a promising therapeutic agent for managing diabetes and its associated complications, including kidney and heart problems.
Paper Details　
Original Abstract of the Article :
Diabetes mellitus is a metabolic disorder caused by either the total destruction of the pancreatic beta cells that secrete insulin for the uptake of glucose from the circulation or as a result of the inability of body cells to respond to the presence of insulin in the blood. The present study invest...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9962974/

データ提供：米国国立医学図書館（NLM）

The Potential of Monodora tenuifolia Seed Extract in Managing Diabetes

This research delves into the potential benefits of a flavonoid-rich fraction of Monodora tenuifolia seed extract (FFMTSE) in managing diabetes. The study used streptozotocin-induced diabetic male Wistar rats to investigate the effects of FFMTSE on blood parameters, particularly those related to lipid profiles, kidney function, and cardiac biomarkers.

FFMTSE Shows Promise in Combating Diabetic Complications

The study revealed that FFMTSE significantly improved blood parameters in diabetic rats. This suggests that FFMTSE may be a potent anti-nephropathy and anti-cardiomyopathy agent in diabetic conditions. FFMTSE significantly improved the observed biochemical parameters in diabetic rats, indicating its potential as an anti-nephropathy and anti-cardiomyopathy agent in diabetic conditions.

A Potential Natural Remedy for Diabetic Complications

This study highlights the potential of natural remedies like FFMTSE in managing diabetic complications. Further research is needed to confirm these findings and explore the potential of FFMTSE as a therapeutic option for people with diabetes.

Dr.Camel's Conclusion

The potential of Monodora tenuifolia seed extract in the desert of diabetic complications is a fascinating discovery. Like a hidden oasis, FFMTSE may offer a natural solution to combat the challenges posed by diabetes. The study's findings require further investigation, but they provide a glimmer of hope for a brighter future for those managing diabetes.
Date :
  1. Date Completed n.d.
  2. Date Revised 2023-03-01
Further Info :

Pubmed ID

36837910

DOI: Digital Object Identifier

PMC9962974

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