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In silico-chemogenomic repurposing of new chemical scaffolds for histoplasmosis treatment.
Author: Borges Dos AnjosLaura Raniere, CostaCarolina Rodrigues, CostaVinícius Alexandre Fiaia, FreitasVivianny Aparecida Queiroz, NevesBruno Junior, SantosAndressa Santana, SilvaMaria do Rosário Rodrigues, ZaraAna Laura de Sene Amâncio
Original Abstract of the Article :
Histoplasmosis is a systemic form of endemic mycosis to the American continent and may be lethal to people living with HIV/AIDS. The drugs available for treating histoplasmosis are limited, costly, and highly toxic. New drug development is time-consuming and costly; hence, drug repositioning is an a...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.mycmed.2023.101363
データ提供:米国国立医学図書館(NLM)
A New Oasis in the Fight Against Histoplasmosis: Drug Repurposing
The fight against [histoplasmosis], a potentially lethal fungal infection, is an ongoing battle. This research explores the exciting world of [drug repurposing], searching for new weapons in the arsenal against this formidable foe. By employing [in silico-chemogenomic] techniques, researchers are seeking to identify new chemical scaffolds that can be repurposed to combat this deadly disease. These strategies offer a promising avenue for developing new therapies, potentially leading to a more effective treatment for patients.
Repurposing Existing Treasures: A New Strategy for Histoplasmosis Treatment
This study explores a promising approach to addressing the limitations of current histoplasmosis treatments. By leveraging existing knowledge and computational tools, researchers are seeking to repurpose existing chemical scaffolds for therapeutic purposes. This innovative strategy holds the potential to accelerate drug development and provide patients with more effective and less toxic treatment options.
A New Hope for Histoplasmosis Patients: Drug Repurposing Offers Potential Solutions
The development of new drug therapies often requires significant time and financial resources. Drug repurposing, however, offers a potential shortcut by leveraging existing knowledge and compounds. This approach has the potential to provide patients with more effective treatment options, which could lead to improved outcomes and reduced costs.
Dr.Camel's Conclusion
The fight against histoplasmosis continues, and drug repurposing offers a promising new avenue for developing effective and affordable therapies. This approach holds the potential to transform the treatment landscape for this challenging disease, offering hope for a brighter future for patients.
Date :
- Date Completed 2023-05-15
- Date Revised 2023-05-15
Further Info :
Related Literature
English
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