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Do the lockdown-imposed changes in a wastewater treatment plant catchment's socio-demographics impact longitudinal temporal trends in psychoactive pharmaceutical use?

Author: AertgeertsBert, BertelsXander, BonmariagePauline, BoogaertsTim, CovaciAdrian, De LoofHans, HamelinckWouter, LahousseLies, PussigBram, QuireynsMaarten, SaevelsJan, Van WichelenNatan, van NuijsAlexander L N

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Wastewater-based epidemiology (WBE) was used to monitor the consumption of antidepressants and opioids in Leuven, Belgium. This approach revealed significant increases in population-normalized mass loads (PNML) of these drugs over the study period. The COVID-19 pandemic, particularly during lockdown phases, was associated with changes in population demographics, leading to variations in PNML.
Paper Details　
Original Abstract of the Article :
Wastewater-based epidemiology (WBE) includes the analysis of human metabolic biomarkers of xenobiotics in influent wastewater. WBE complements existing drug utilization approaches and provides objective, spatio-temporal information on the consumption of pharmaceuticals in the general population. Thi...See full text at original site
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引用元：
https://doi.org/10.1016/j.scitotenv.2023.162342

データ提供：米国国立医学図書館（NLM）

Wastewater-Based Epidemiology: A Window into the Desert of Psychoactive Drug Use

Wastewater-based epidemiology (WBE) is an innovative tool for monitoring drug use patterns within a population. Imagine a desert oasis, where the flow of water reveals the secrets of the surrounding environment. This study uses WBE to investigate the longitudinal temporal trends of psychoactive pharmaceutical use in a wastewater treatment plant catchment area, revealing patterns of drug consumption within the community.

A Window into the Desert: Monitoring Drug Use Patterns

The study analyzed 24-hour composite influent wastewater samples from Leuven, Belgium, over a period of three years, measuring concentrations of 21 biomarkers for antidepressant and opioid use. The results revealed a significant increase in the population-normalized mass loads (PNML) of most biomarkers, indicating a growing trend in the use of these medications.

The Shifting Sands of Drug Use: Influences on Consumption Patterns

The study identified a significant impact of population disruption during the COVID-19 pandemic on the PNML of various biomarkers. The changing demographics of the catchment area, driven by population movements, influenced drug consumption patterns. This finding highlights the importance of considering social and environmental factors when analyzing drug use trends. It's like observing the shifting sands of a desert landscape, revealing the underlying forces that shape the environment.

Dr.Camel's Conclusion

This study demonstrates the effectiveness of WBE as a tool for monitoring drug use patterns within a community. The analysis revealed significant temporal trends in psychoactive pharmaceutical use, highlighting the influence of population dynamics on drug consumption. This approach offers a valuable window into the desert of drug use, providing insights into the social and environmental factors that influence medication use.

Date :
  1. Date Completed 2023-05-01
  2. Date Revised 2023-05-01
Further Info :

Pubmed ID

36842581

DOI: Digital Object Identifier

10.1016/j.scitotenv.2023.162342

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