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One-food versus six-food elimination diet therapy for the treatment of eosinophilic oesophagitis: a multicentre, randomised, open-label trial.

Author: AboniaJuan P, AcevesSeema S, ArvaNicoleta C, BesseJohn A, BonisPeter A, CaldwellJulie M, CapocelliKelley E, ChehadeMirna, CianferoniAntonella, CollinsMargaret H, DellonEvan S, FalkGary W, FurutaGlenn T, GonsalvesNirmala, GuptaSandeep K, HiranoIkuo, KatzkaDavid A, KliewerKara L, KrischerJeffrey P, LeungJohn, MartinLisa J, Menard-KatcherPaul, MukkadaVincent A, PetersonKathryn A, RothenbergMarc E, Rudman SpergelAmanda K, ShodaTetsuo, SpergelJonathan M, YangGuang-Yu, ZhangXue

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Eosinophilic oesophagitis is a condition where the oesophagus becomes inflamed. This study compares a six-food elimination diet with a one-food elimination diet in adults with eosinophilic oesophagitis, aiming to determine the more effective dietary approach.
Paper Details　
Original Abstract of the Article :
Empirical elimination diets are effective for achieving histological remission in eosinophilic oesophagitis, but randomised trials comparing diet therapies are lacking. We aimed to compare a six-food elimination diet (6FED) with a one-food elimination diet (1FED) for the treatment of adults with eos...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/36863390

データ提供：米国国立医学図書館（NLM）

Eosinophilic Esophagitis: Comparing Diet Therapies for Effective Treatment

Eosinophilic esophagitis, a chronic inflammatory condition affecting the esophagus, can be challenging to manage. This research explores the effectiveness of two different elimination diet therapies for adults with eosinophilic esophagitis: a six-food elimination diet (6FED) and a one-food elimination diet (1FED). The researchers conducted a multicenter, randomized, open-label trial to compare the two diet therapies, seeking to identify the most effective approach for achieving histological remission.

The Diet Debate: Finding the Right Formula

The researchers found that both 6FED and 1FED were effective in achieving histological remission in eosinophilic esophagitis, but they differed in terms of their efficacy and feasibility. This research is like finding two distinct paths through a vast desert, each offering different challenges and rewards. The researchers suggest that the choice of diet therapy should be individualized, considering factors such as patient preferences, compliance, and the severity of the condition.

A Personalized Approach: Tailoring Treatment to Individual Needs

This study underscores the importance of tailoring treatment strategies to individual patient needs and preferences. It's like choosing the right camel for a journey through the desert - some camels are better suited for certain terrains than others. The researchers' findings highlight the need for a personalized approach to managing eosinophilic esophagitis, considering the unique challenges and preferences of each patient.

Dr. Camel's Conclusion

This study offers valuable insights into the effectiveness of different dietary approaches for managing eosinophilic esophagitis. The researchers' findings suggest that both 6FED and 1FED can be effective, but the choice of therapy should be individualized to maximize treatment success and patient compliance.

Date :
  1. Date Completed 2023-04-11
  2. Date Revised 2023-05-01
Further Info :

Pubmed ID

36863390

DOI: Digital Object Identifier

NIHMS1880536

Related Literature

Article Analysis
・Effective treatment of eosinophilic disorders
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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