Paper Details

  1. Home
  2. Paper Details

Persistence of Biologics in the Treatment of Psoriatic Arthritis: Data From a Large Hospital-Based Longitudinal Cohort.

Author: ChandranVinod, CookRichard J, GladmanDafna D, LeeKer-Ai, RidaMohamad-Ali

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

A retrospective analysis of 571 patients with psoriatic arthritis found that drug persistence varied depending on whether the biologic was used as first or second treatment. Depression, anxiety, higher tender joint count, and older age were associated with higher rates of drug discontinuation.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To analyze the trends in biologics use at a specialized center over a period of 20 years. METHODS: We performed a retrospective analysis of 571 patients diagnosed with psoriatic arthritis enrolled in the Toronto cohort who initiated biologic therapy between January 1, 2000, and July 7, 2...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1002/acr.25112

データ提供：米国国立医学図書館（NLM）

Persistence of Biologics in the Treatment of Psoriatic Arthritis: A Long-Term Perspective

We're exploring the long-term effectiveness of [biologics] in treating [psoriatic arthritis]. This study investigates the persistence of biologics use in a large cohort of patients over a 20-year period. Imagine a camel caravan traversing a vast desert of time, seeking to understand the lasting effects of these potent therapies.

Biologic Persistence in Psoriatic Arthritis: Factors Influencing Treatment Duration

The study found that persistence with biologics varied significantly depending on the specific drug and its position in the treatment sequence. It also identified factors that can influence drug discontinuation, including patient characteristics such as [depression] and [anxiety].

Optimizing Biologic Therapy for Psoriatic Arthritis: A Long-Term Approach

This study highlights the importance of long-term monitoring and personalized management of [psoriatic arthritis] patients receiving biologics. It's a reminder that the desert of [psoriatic arthritis] treatment is complex and requires a comprehensive approach to care.

Dr. Camel's Conclusion

This study offers valuable insights into the long-term use of biologics in treating [psoriatic arthritis]. It's a reminder that the desert of chronic illness management is often a journey, and we need to understand the factors that can influence treatment persistence to ensure the best possible outcomes for patients.
Date :
  1. Date Completed 2023-10-23
  2. Date Revised 2023-11-03
Further Info :

Pubmed ID

36913183

DOI: Digital Object Identifier

10.1002/acr.25112

Related Literature

Article Analysis
・Causes of psoriatic arthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.