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Dupuytren's Contracture Recurrence and Treatment Following Collagenase Clostridium Histolyticum Injection: A Longitudinal Assessment in a Veteran Population.

Author: DaleyRoger A, GrafAlexander R, MatloubHani S, SangerJames R, StehrRyan C, TalhelmJacob E, ZarbRakel M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study aims to evaluate factors predictive of recurrence following treatment with collagenase clostridium histolyticum (CCH) for Dupuytren's contracture and to review the outcomes of repeat treatments with CCH for recurrent contracture.
Paper Details　
Original Abstract of the Article :
Dupuytren's contracture is a connective tissue disease characterized by an abnormal proliferation of collagen in the palm and fingers, which leads to a decline in hand function because of progressive joint flexion. In addition to surgical and percutaneous interventions, collagenase clostridium histo...See full text at original site
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引用元：
https://doi.org/10.1093/milmed/usad075

データ提供：米国国立医学図書館（NLM）

Dupuytren's Contracture: Addressing Recurrence after Collagenase Clostridium Histolyticum Injection

Dupuytren's contracture, a debilitating condition affecting the hand, can lead to progressive joint flexion, making everyday tasks a challenge. [Collagenase Clostridium Histolyticum (CCH)] is a relatively new treatment option for Dupuytren's contracture, but concerns about its efficacy and recurrence rates remain. This study investigates the factors that contribute to recurrence after CCH treatment and examines the outcomes of repeat treatments for those who experience recurrent contracture.

Understanding Recurrence Rates and Treatment Options

This study aims to help doctors identify patients who are at higher risk of experiencing Dupuytren's contracture recurrence after CCH treatment. It also explores the potential benefits and risks of repeat treatments with CCH.

Living with Dupuytren's Contracture: A Journey of Hope and Resilience

As a camel, I have seen my fair share of challenges and endured the occasional thorn in my hoof. The journey of living with Dupuytren's contracture can be similar, but advancements in treatments, like CCH, offer hope for those seeking relief from this condition.

Dr.Camel's Conclusion

This research is a valuable step towards understanding Dupuytren's contracture and the effectiveness of CCH treatment. It highlights the need for continued research to identify factors that influence recurrence and develop strategies for managing the condition more effectively.

Date :
  1. Date Completed 2023-08-31
  2. Date Revised 2023-09-16
Further Info :

Pubmed ID

36928340

DOI: Digital Object Identifier

10.1093/milmed/usad075

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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