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Case Series of Precision Delivery of Methylprednisolone in Pediatric Inflammatory Bowel Disease: Feasibility, Clinical Outcomes, and Identification of a Vasculitic Transcriptional Program.
Author: FrancBenjamin, GangulyAbantika, GoyalAlka, GubatanJohn, GugigRoberto, LevitteSteven, MartinLynne, NadelHelen R, ParkK T, SyedAli, ThakorAvnesh S, YaraniReza
Original Abstract of the Article :
Systemic steroid exposure, while useful for the treatment of acute flares in inflammatory bowel disease (IBD), is associated with an array of side effects that are particularly significant in children. Technical advancements have enabled locoregional intraarterial steroid delivery directly into spec...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10053508/
データ提供:米国国立医学図書館(NLM)
Precision Delivery of Methylprednisolone: A New Oasis in the Desert of Pediatric Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a challenging condition, especially for children, who may experience significant side effects from systemic steroid treatment. This case series explores the feasibility and outcomes of locoregional intraarterial methylprednisolone delivery directly into the bowel for pediatric IBD patients. The authors found that this approach provided symptom relief in all patients, with sustained relief in most, and no serious adverse effects. This innovative approach offers a promising strategy for minimizing systemic steroid exposure and improving the management of pediatric IBD.
Navigating the Sands of Pediatric IBD: A Targeted Approach
The study's findings suggest that intraarterial steroid delivery could be a valuable alternative to systemic steroid treatment for pediatric IBD patients. This targeted approach allows for higher tissue concentrations while minimizing systemic exposure, potentially reducing the risk of side effects. The study's results offer a promising new avenue for managing this complex condition and improving the lives of children with IBD.
Living in the Oasis: Managing Pediatric IBD Effectively
The desert of IBD can be a challenging landscape for children, but this study offers a glimmer of hope for a more effective and less burdensome treatment approach. This innovative technique could revolutionize the management of pediatric IBD, offering a path towards improved quality of life and minimized side effects. It's essential to consult with a healthcare professional to determine the best treatment options for your child's individual needs.
Dr.Camel's Conclusion
The desert of pediatric IBD can be a difficult place for children and their families to navigate. This study provides a promising oasis, highlighting the potential of precision delivery of methylprednisolone to improve the management of this complex condition. It's a reminder that with innovative approaches and continued research, we can find more effective and less burdensome treatments for children facing the challenges of IBD.
Date :
- Date Completed n.d.
- Date Revised 2023-03-31
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