Efficacy and safety of Propionibacterium extract gel versus glyceryl trinitrate ointment in the treatment of chronic anal fissure: a randomized controlled trial.

Author: AltomareDonato Francesco, CantarellaFrancesco, CurròGiuseppe, FulginitiSerena, GalloGaetano, GrossiUgo, La TorreMarco, RinaldiMarcella, SantoroGiulio Aniello, TiernoSimone, TomasicchioGiovanni, TrompettoMario, VaniniPaolo

Paper Details 
Original Abstract of the Article :
Chronic anal fissure (CAF) is an extremely frequent finding in clinical practice. Several topical agents have been proposed for its treatment with the common goal of increasing anodermal blood flow to promote healing. The aim of this study was to compare the efficacy and safety of a Propionibacteriu...See full text at original site
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引用元:
https://doi.org/10.1111/codi.16576

データ提供:米国国立医学図書館(NLM)

Chronic Anal Fissure Treatment: Comparing Propionibacterium Extract Gel and Glyceryl Trinitrate Ointment

The field of [proctology] is constantly seeking effective treatments for [chronic anal fissure], a common and often painful condition. This research compares the efficacy and safety of two topical agents: [Propionibacterium extract gel (PeG)] and [0.4% glyceryl trinitrate ointment (GTN)]. The authors conducted a randomized controlled trial, investigating the therapeutic effectiveness of these agents in patients with [chronic anal fissure]. Their findings provide valuable insights into the relative effectiveness of these treatments and offer guidance for clinicians managing patients with this condition.

A New Approach to Chronic Anal Fissure Treatment: Exploring the Potential of Propionibacterium Extract Gel

The findings of this study suggest that [Propionibacterium extract gel (PeG)] may be an effective and safe treatment option for [chronic anal fissure]. The authors observed promising results with [PeG] therapy, highlighting its potential to improve [anodermal blood flow] and promote healing. This research provides valuable insights into the potential of [PeG] as a new therapeutic option for patients with [chronic anal fissure].

Living with Chronic Anal Fissure: Seeking Relief and Promoting Healing

[Chronic anal fissure] can be a painful and debilitating condition, but advancements in treatment offer hope for patients. This research underscores the importance of seeking early diagnosis and treatment to maximize the potential for successful outcomes. By working closely with healthcare professionals and exploring all available treatment options, patients with [chronic anal fissure] can manage their condition and strive for a healthier future. This research offers a beacon of hope for patients with [chronic anal fissure], highlighting the potential for effective treatment and improved quality of life.

Dr. Camel's Conclusion

This research on the treatment of [chronic anal fissure] provides valuable insights into the ongoing quest for effective and safe therapies. Like a desert explorer seeking a life-giving oasis, researchers in the field of [proctology] are continually searching for better treatments for this common condition. The findings of this study offer a promising step forward in this journey, highlighting the potential of [Propionibacterium extract gel (PeG)] as a new therapeutic option for patients with [chronic anal fissure]. This research underscores the importance of ongoing research and innovation in the fight against this debilitating condition.

Date :
  1. Date Completed 2023-08-17
  2. Date Revised 2023-08-17
Further Info :

Pubmed ID

37029603

DOI: Digital Object Identifier

10.1111/codi.16576

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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