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Prenatal Morphine Exposure Increases Cardiovascular Disease Risk and Programs Neurogenic Hypertension in the Adult Offspring.

Author: AhmedNermin, BardoMichael, DalmassoCarolina, GongMing C, GordonScott M, KassisAlana, LinAn-Hsuan, LoriaAnalia S, MaloneJena, YangJodie, ZamzamiEsraa

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.

Overview

This study investigated the impact of in utero morphine exposure on offspring cardiovascular health, finding an increased risk of CVD risk factors and dysregulation of the endogenous opioid system, highlighting the long-term consequences of opioid use during pregnancy.
Paper Details　
Original Abstract of the Article :
The opioid overdose and opioid use disorder epidemics are concomitant with increased metabolic and CVD risk. Although opioid use disorder causes adverse pregnancy outcomes, the offspring's cardiovascular health is understudied. We hypothesized that offspring exposed to in utero morphine exposure (IU...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/37042247

データ提供：米国国立医学図書館（NLM）

Prenatal Morphine Exposure: A Desert of Potential Cardiovascular Risk

The opioid epidemic has cast a long shadow on our society, leaving a trail of devastation in its wake. This study explores the impact of prenatal morphine exposure (IUME) on the cardiovascular health of offspring, highlighting a potential link between IUME and increased cardiovascular disease risk. The authors found that IUME significantly increased cardiovascular risk factors and programmed neurogenic hypertension in the adult offspring, suggesting that exposure to opioids during pregnancy could have long-lasting consequences on the health of the next generation.

A Legacy of Risk: Prenatal Morphine Exposure and Cardiovascular Health

This study provides compelling evidence for a potential link between prenatal morphine exposure and increased cardiovascular disease risk in the offspring. It underscores the importance of addressing the opioid epidemic and the need for comprehensive strategies to mitigate the potential long-term health consequences of IUME.

Navigating the Desert of Opioid Dependence: A Call for Action

The opioid crisis is a complex and challenging desert, demanding a multifaceted approach to address its devastating consequences. This study highlights the potential long-term health risks associated with prenatal opioid exposure, urging us to prioritize prevention, treatment, and support for pregnant women struggling with opioid dependence.

Dr.Camel's Conclusion

The opioid epidemic is a vast and unforgiving desert, leaving a trail of devastation in its wake. This study sheds light on the potential long-term health consequences of prenatal morphine exposure, highlighting the urgent need for proactive measures to mitigate the impact of opioid use disorder on future generations. It underscores the importance of addressing this complex issue with a focus on prevention, treatment, and support for individuals and families affected by this crisis.
Date :
  1. Date Completed 2023-05-19
  2. Date Revised 2023-06-19
Further Info :

Pubmed ID

37042247

DOI: Digital Object Identifier

NIHMS1885698

Related Literature

Article Analysis
・Causes of opioid use
SNS
PICO Info
in preparation
Languages

English

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