Oral Capecitabine Exposures and Use of Uridine Triacetate: A 20-Year Retrospective Analysis.

Author: CantrellF Lee, FriedmanNathan A, GalustHenrik, HardinJeremy, MinnsAlicia, SeltzerJustin A

Paper Details 
Original Abstract of the Article :
Capecitabine is an oral prodrug of 5-fluorouracil. Toxicity can occur during therapy as well as acutely with overdose and particular genetic susceptibilities. Uridine triacetate is an effective antidote if given within 96 h of exposure. This study seeks to characterize accidental and intentional cap...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198921/

データ提供:米国国立医学図書館(NLM)

Navigating the Landscape of Capecitabine Toxicity

Cancer treatment often involves potent drugs that can have significant side effects. This study focuses on capecitabine, an oral chemotherapy drug used to treat various cancers. The researchers analyze real-world data to understand the patterns of accidental and intentional capecitabine exposure and the role of uridine triacetate, an antidote for capecitabine toxicity. This study is critical in informing healthcare professionals and patients about the potential risks and management strategies associated with capecitabine treatment.

Understanding Capecitabine Toxicity and Management

The study highlights the importance of early recognition and prompt treatment of capecitabine toxicity. Uridine triacetate is an effective antidote when administered within 96 hours of exposure. This knowledge is vital for healthcare professionals, allowing them to intervene swiftly and mitigate the potential harmful effects of capecitabine overdose. It's like having a trusty oasis in the desert of potential complications, providing a source of relief and recovery.

Living with Cancer: A Journey Through the Desert

Cancer treatment can be a challenging journey, often accompanied by side effects. This study sheds light on the potential risks and management strategies associated with capecitabine therapy. It reminds us that while cancer treatment is crucial, it's equally important to be aware of potential complications and have access to effective countermeasures. It's like having a map and a compass to navigate the challenging landscape of cancer treatment, ensuring a safer and smoother path to recovery.

Dr.Camel's Conclusion

This study emphasizes the importance of vigilant monitoring and prompt intervention in managing capecitabine-related toxicity. It's like having a watchful camel guide, always alert to potential dangers and ready to provide swift support when needed. The insights gained from this research can help us better understand and manage the potential challenges of cancer treatment, ultimately enhancing the well-being of patients.

Date :
  1. Date Completed 2023-05-22
  2. Date Revised 2023-07-21
Further Info :

Pubmed ID

37072662

DOI: Digital Object Identifier

PMC10198921

Related Literature

SNS
PICO Info
in preparation
Languages

English

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