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Serositis causing pericardial and pleural effusions after eight years of maintenance ibrutinib for Waldenstrom's macroglobulinemia.
Author: BaviriseatyNiharika, JohnsonGrace, KooperJeffrey, MassanetNicholas
Original Abstract of the Article :
Ibrutinib is a tyrosine kinase inhibitor approved for multiple B-cell malignancies, including Waldenstrom's macroglobulinemia in 2014. Although the drug portends favorable outcomes, it also bears a profile of side effects. Current literature describes only two cases of nonhemorrhagic pericardial eff...See full text at original site
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引用元:
https://doi.org/10.1177/10781552231171925
データ提供:米国国立医学図書館(NLM)
Serositis: An Unexpected Side Effect of Ibrutinib
The [hematology] world is constantly seeking to improve treatment options for [Waldenstrom's macroglobulinemia (WM)], a rare type of non-Hodgkin lymphoma. This research presents a case report of a patient who developed [serositis] causing [pericardial and pleural effusions] and [diffuse edema] after eight years of maintenance [ibrutinib] therapy for [WM]. The study used a [case report] approach to describe this unusual side effect.
An Uncommon but Significant Side Effect
This research highlights the potential for [serositis] to occur as an unexpected side effect of [ibrutinib] therapy, even after long-term use. While [ibrutinib] has proven to be an effective treatment for [WM], this case report underscores the importance of being aware of potential side effects and closely monitoring patients for any signs or symptoms of [serositis]. Early recognition and treatment of [serositis] can help to prevent complications and ensure the best possible outcomes for patients.
Navigating the Sands of Long-Term Ibrutinib Therapy
This research reminds us that even in the desert of long-term [ibrutinib] therapy, unexpected challenges can arise. The authors' findings highlight the importance of careful monitoring for potential side effects and the need to be vigilant in detecting early signs of [serositis]. By understanding the potential risks and benefits of [ibrutinib] therapy, patients and their healthcare providers can work together to make informed decisions and manage treatment effectively.
Dr. Camel's Conclusion
The study emphasizes the importance of remaining vigilant even in the face of successful long-term treatment. While ibrutinib has revolutionized the treatment of Waldenstrom's macroglobulinemia, we must remain aware of its potential side effects. Just as a traveler in the desert must constantly watch for mirages and hidden dangers, we must remain vigilant in monitoring patients for any unexpected complications. This case report serves as a reminder to stay informed, collaborate closely, and navigate the terrain of long-term therapy with caution and care.
Date :
- Date Completed n.d.
- Date Revised 2023-04-25
Further Info :
Related Literature
English
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