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Pharmacogenomics on the Treatment Response in Patients with Psoriasis: An Updated Review.

Author: ChangYa-Ching, ChenChun-Bing, ChenWei-Ti, ChungWen-Hung, HuiRosaline Chung-Yee, WangChing-Ya, WangChuang-Wei

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review highlights the current pharmacogenetic and pharmacogenomic studies of medical therapy in psoriasis. It discusses the potential of pharmacogenomics in predicting treatment response based on genetic predisposition. While HLA-Cw*06 status remains a strong predictor for certain drugs, other genetic variants are also being investigated for their role in treatment response.
Paper Details　
Original Abstract of the Article :
The efficacy and the safety of psoriasis medications have been proved in trials, but unideal responses and side effects are noted in clinical practice. Genetic predisposition is known to contribute to the pathogenesis of psoriasis. Hence, pharmacogenomics gives the hint of predictive treatment respo...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138383/

データ提供：米国国立医学図書館（NLM）

Pharmacogenomics: Unlocking the Secrets of Personalized Psoriasis Treatment

Psoriasis is a chronic skin condition that affects millions worldwide. While various medications are available to manage psoriasis, individual responses to treatment can vary significantly. This review examines the emerging field of pharmacogenomics, exploring how genetic factors can influence treatment outcomes in patients with psoriasis. The authors delve into the potential of pharmacogenomics to predict treatment response and optimize individual care.

A New Era of Personalized Medicine: Pharmacogenomics in Psoriasis

The review highlights the potential of pharmacogenomics to personalize psoriasis treatment, identifying genetic factors that influence drug efficacy and side effect profiles. [Pharmacogenomics's potential in psoriasis treatment]. These findings pave the way for a more individualized approach to psoriasis management, leading to improved treatment outcomes and patient satisfaction.

A Camel's Perspective on Personalized Medicine

Imagine a camel crossing a desert, its journey tailored to its unique abilities and needs. Personalized medicine is a similar approach to healthcare, recognizing that individuals respond differently to treatments. This review explores the potential of pharmacogenomics in psoriasis treatment, offering a personalized approach that considers each patient's genetic makeup. Just as a camel's journey is guided by its innate strengths, personalized medicine aims to tailor treatments to each individual's unique characteristics, maximizing their chances of a successful outcome.

Dr. Camel's Conclusion

This review underscores the promise of pharmacogenomics in revolutionizing psoriasis treatment. By understanding the genetic factors that influence drug response, healthcare providers can tailor treatments to each individual patient, leading to more effective and personalized care. Continued research in pharmacogenomics holds exciting possibilities for transforming the management of psoriasis and other chronic diseases.

Date :
  1. Date Completed 2023-05-01
  2. Date Revised 2023-05-01
Further Info :

Pubmed ID

37108492

DOI: Digital Object Identifier

PMC10138383

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Languages

English

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