Effects of hyaluronic acid and chondroitin sulfate on acute radiation proctitis in rats.

Author: AlanyaliSenem, CalıskanCemil, CinSamed, DoganavsargilBasak, Kuvvet YoldasTuba, SezakMurat, Solakİlhami, YoldasMehmet, YoldasTayfun

Paper Details 
Original Abstract of the Article :
BACKGROUND: This study was designed to investigate the prophylactic and therapeutic effects of hyaluronic acid and chondroitin sulfate combination (HA/CS) on a model of acute radiation proctitis. METHODS: Rats were divided into five groups: SHAM; irradiation (IR) + saline (1 mL for 5th and 10th day...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10277333/

データ提供:米国国立医学図書館(NLM)

Hyaluronic Acid and Chondroitin Sulfate: A Potential Oasis for Radiation Proctitis?

This study delves into the fascinating realm of radiation proctitis, a condition that can be as uncomfortable as traversing a scorching desert without a camel! It investigates the prophylactic and therapeutic effects of a combination of hyaluronic acid and chondroitin sulfate (HA/CS) in a rat model. This is like offering a refreshing sip of water to a parched traveler, except in this case, it's a potential remedy for the irritated lining of the rectum.

HA/CS: A Beacon of Hope for Radiation Proctitis?

The study found that HA/CS offered significant protection against radiation-induced damage to the rectal lining. This is particularly promising given the debilitating symptoms that can accompany radiation proctitis, which can be as troublesome as navigating a sandstorm. The researchers observed that the HA/CS group showed less inflammation and fewer crypt changes compared to the saline-treated group.

A Glimpse into the Desert Oasis of Relief

HA/CS might hold the key to alleviating the discomfort of radiation proctitis. It seems like a promising oasis in the desert of this challenging condition, offering a potential source of relief for those who experience its harsh realities.

Dr. Camel's Conclusion

This research suggests that HA/CS might be a valuable therapeutic agent for radiation proctitis, potentially improving the quality of life for those who suffer from this condition. It's a promising direction for future research, and I can't wait to see what other hidden treasures we might uncover in this fascinating area of medicine.
Date :
  1. Date Completed 2023-05-08
  2. Date Revised 2023-06-21
Further Info :

Pubmed ID

37145048

DOI: Digital Object Identifier

PMC10277333

Related Literature

SNS
PICO Info
in preparation
Languages

English

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