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A Review on the Efficacy and Safety of Intrathecal Administration of Novel Medications for Leptomeningeal Metastases in Solid Cancers.

Author: ArastehOmid, AzadSajad, BahararaHamed, HosseinjaniHesamoddin, JafariFatemeh, JohnstonThomas P, NodehMohammad Moeini, SahebkarAmirhossein

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Leptomeningeal disease (LMD) is a rare and serious complication of cancer, occurring in the advanced stages of solid tumors and hematological malignancies. While treatment is challenging, intrathecal administration of novel therapeutics is a promising strategy to complement other therapies. This review examines the effects of intrathecally administered medications for LMD, highlighting the potential benefits and need for further clinical evaluation.
Paper Details　
Original Abstract of the Article :
Leptomeningeal disease (LMD) is a rare and lethal manifestation that may occur in the advanced stages of solid tumors and hematological malignancies. With advances in diagnostic techniques, the detection and confirmation of the presence of LMD have increased. Although its optimal treatment remains a...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.2174/0929867330666230508142657

データ提供：米国国立医学図書館（NLM）

Intrathecal Administration of Novel Medications for Leptomeningeal Metastases: Exploring New Pathways in the Desert of Cancer Treatment

The desert of cancer treatment can be a challenging and often unforgiving landscape. Leptomeningeal disease (LMD), a rare and often lethal complication of cancer, poses a significant challenge for healthcare providers. This research explores the potential of intrathecal administration of novel medications for the treatment of LMD. The researchers reviewed the available literature, highlighting the promising role of intrathecal therapy in managing LMD, particularly in metastatic breast and lung cancer.

A Potential Breakthrough in Cancer Treatment

This research underscores the potential of intrathecal administration of novel medications as a promising new approach for treating LMD. The authors highlight the effectiveness of this approach in managing symptoms and extending lifespan in patients with LMD. While further research is needed, this research offers a beacon of hope in the desert of cancer treatment.

Navigating the Desert of Cancer Treatment

The desert of cancer treatment can be a challenging and often emotional journey. It is crucial to seek the guidance of healthcare professionals and explore all available treatment options. This research, while focusing on LMD, emphasizes the importance of continued research and innovation in the field of cancer treatment, seeking new and effective ways to fight this debilitating disease.

Dr.Camel's Conclusion

This research, like a trailblazer navigating the desert of cancer treatment, explores new and promising pathways for treating LMD. It reminds us that the search for effective treatments is an ongoing journey, and that innovation and persistence are key to finding solutions in the face of challenging health conditions.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-05-09
Further Info :

Pubmed ID

37157199

DOI: Digital Object Identifier

10.2174/0929867330666230508142657

SNS
PICO Info
in preparation
Languages

English

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