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Clinical characteristics of 32 cases of diffuse panbronchiolitis.

Author: CaoYing, ChenZhifeng, HuHui, OuYanru, OuyangRuoyun, ShenChong, ZhangLianhua

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This study summarized the clinical characteristics and treatment of diffuse panbronchiolitis (DPB). DPB is a chronic airway inflammation with low specificity and its diagnosis is often missed or delayed. The study found that all patients presented with chronic cough and copious sputum production. A total of 26 patients had post activity shortness of breath and 14 patients had a positive result (blood cold agglutination test titer≥1꞉64). All patients were treated with macrolides. A total of 31 patients showed improvement, and 20 patients showed improvement in partial pressure of oxygen and blood oxygen saturation compared with before at discharge. The clinical manifestations of DPB are nonspecific. Early diagnosis and treatment are very important for the prognosis of patients.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: Diffuse panbronchiolitis (DPB) is a chronic airway inflammation with low specificity and its diagnosis is often missed or delayed. This study aims to summarize the clinical characteristics and treatment of DPB in order to improve the understanding and diagnosis of the disease. METHODS: ...See full text at original site
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引用元：
https://doi.org/10.11817/j.issn.1672-7347.2023.220309

データ提供：米国国立医学図書館（NLM）

Unveiling the Mystery of Diffuse Panbronchiolitis: A Clinical Analysis of 32 Cases

This study analyzes the [clinical characteristics and treatment of diffuse panbronchiolitis (DPB)]. DPB is a chronic inflammatory condition of the airways with [low specificity], making diagnosis challenging. The study aims to improve understanding and diagnosis of DPB by summarizing the clinical features and treatment outcomes observed in a cohort of 32 patients.

Understanding the Clinical Profile of Diffuse Panbronchiolitis

The researchers found [a median age of symptom onset at 26.5 years and a median age of diagnosis at 47.5 years]. All patients presented with [chronic cough and sputum production]. The study also found that [pulmonary function tests revealed mixed pulmonary ventilation dysfunction, obstructive pulmonary ventilation, or normal function]. Additionally, [chest CT imaging showed a bilateral, diffuse, small nodule pattern in most patients]. These findings provide a detailed clinical profile of DPB, which can aid in early diagnosis and treatment.

Early Diagnosis and Treatment: Keys to Prognosis

The study emphasizes the importance of [early diagnosis and treatment] for DPB. The findings suggest that [prompt initiation of treatment with macrolides can lead to improvement in symptoms and lung function]. However, [the disease progression can still occur in some patients even after treatment]. Therefore, continued monitoring and follow-up are crucial to ensure optimal patient outcomes. The researchers suggest that [further research is needed to explore more effective treatment options and prevent disease progression].

Dr.Camel's Conclusion

This study helps us understand the intricate nature of DPB, a condition that can be challenging to diagnose. It is like navigating a dense desert, where hidden dangers and unpredictable weather patterns can pose significant threats. This research offers a roadmap for identifying and treating DPB, providing hope for patients who face this challenging condition. It emphasizes the importance of vigilant monitoring and continued research to ensure the best possible care.

Date :
  1. Date Completed 2023-05-12
  2. Date Revised 2023-05-12
Further Info :

Pubmed ID

37164916

DOI: Digital Object Identifier

10.11817/j.issn.1672-7347.2023.220309

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