Paper Details 
Original Abstract of the Article :
Extratympanic electrocochleography was performed on three patients following tobramycin injection and ten patients during cisplatin (cis-dichlorodiamine platinum II infusion. The compound eighth nerve action potential and the cochlear microphonic decreased considerably in magnitude up to 45 to 60 mi...See full text at original site
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引用元:
https://doi.org/10.1001/archotol.1986.03780080023004

データ提供:米国国立医学図書館(NLM)

Cisplatin and the Cochlea: A Delicate Dance in the Desert of Hearing

The intricate world of hearing, a delicate ecosystem within the vast desert of the human body, is easily disrupted. This study delves into the potential effects of cisplatin, a chemotherapy drug, on the cochlea, the inner ear structure responsible for sound processing. The researchers used electrocochleography to monitor the cochlear output in patients undergoing cisplatin infusion. They found that while tobramycin, another drug, caused significant changes in cochlear function, cisplatin did not have a notable impact on the cochlear response. This research suggests that cisplatin may have a lower risk of ototoxicity, the damage to the auditory system, compared to tobramycin. This finding has important implications for managing the side effects of chemotherapy and preserving hearing function.

Cisplatin and Ototoxicity: A Delicate Balance in the Desert

This study offers insights into the potential ototoxicity of cisplatin, a chemotherapy drug commonly used to treat various cancers. The researchers found that cisplatin did not significantly affect cochlear function in their study, suggesting a lower risk of hearing loss compared to another drug, tobramycin. These findings have implications for managing the side effects of cisplatin and preserving hearing function in patients undergoing chemotherapy. It's like navigating a desert, knowing that certain paths may be more treacherous than others, and seeking ways to minimize potential hazards.

Hearing Health and Chemotherapy: A Careful Journey Through the Desert

This study highlights the importance of carefully monitoring hearing function in patients undergoing chemotherapy, particularly those receiving cisplatin. The findings suggest that cisplatin may have a lower risk of ototoxicity compared to other drugs, but it's crucial to be vigilant in detecting and managing any potential hearing loss. It's like navigating a desert with a keen eye for signs of danger, ensuring a safe and successful journey.

Dr. Camel's Conclusion

This study reminds us that the desert of chemotherapy treatment can be fraught with challenges, including potential damage to the hearing system. However, the study offers a glimmer of hope, suggesting that cisplatin may have a lower risk of ototoxicity compared to other drugs. It's like finding a pathway through the desert that minimizes the risk of encountering dangerous sandstorms.

Date :
  1. Date Completed 1986-08-20
  2. Date Revised 2019-08-24
Further Info :

Pubmed ID

3718685

DOI: Digital Object Identifier

10.1001/archotol.1986.03780080023004

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SNS
PICO Info
in preparation
Languages

English

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