Opioid Agents and Cardiac Arrhythmia: A Literature Review.

Author: Akbar Gafur UgliBazarbaev, GolibkhonAzamatov, Makhamadjonov Farkhod UgliMuzaffar

Paper Details 
Original Abstract of the Article :
Opioids are compounds that cause similar effects to morphine by binding to its receptors. Opioids can be synthetic, semi-synthetic, or natural and can easily bind to the receptors of opioids in order to depict their effects, which may vary depending upon the exposure of the drug and its dose. Howeve...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10207988/

データ提供:米国国立医学図書館(NLM)

Opioids and the Heart: A Delicate Dance

This research delves into the fascinating yet perilous relationship between opioids and the heart's electrical activity. It's like a slow, rhythmic dance where the music, represented by opioids, can either set the pace for a graceful waltz or lead to a chaotic, unpredictable tango. This study, using an extensive literature review, investigated the impact of different opioids on the heart's electrical activity, specifically focusing on their potential to disrupt the heart's natural rhythm.

Opioids and Heart Rhythm: A Balancing Act

The study reveals a fascinating spectrum of effects. Opioids like methadone, even in small doses, were found to be the most potent in prolonging the QT interval, a measure of heart rhythm, and potentially leading to irregular heartbeats. Other opioids, such as oxycodone and tramadol, fall into a middle ground, posing a risk of disrupting heart rhythm in larger doses. Conversely, opioids like buprenorphine and morphine are considered low risk, showing minimal impact on heart rhythm in typical doses.

A Gentle Reminder: Listen to Your Heart

This research underscores the importance of careful monitoring, especially for individuals taking higher doses of opioids. Regular electrocardiograms, like a heart's own compass, can help track any potential disruptions in heart rhythm and provide early warning signs. It also emphasizes the need for a personalized approach, recognizing that each individual's response to opioids can vary.

Dr.Camel's Conclusion

This study serves as a valuable compass for healthcare professionals navigating the complex terrain of opioid use and cardiac health. It highlights the delicate dance between these two systems and emphasizes the importance of a personalized approach to medication management. Just like a skilled dancer, healthcare providers must carefully monitor and adjust their steps, ensuring a harmonious rhythm for their patients' well-being.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-05-28
Further Info :

Pubmed ID

37228540

DOI: Digital Object Identifier

PMC10207988

Related Literature

SNS
PICO Info
in preparation
Languages

English

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