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Topical Delivery of Ketorolac Tromethamine via Cataplasm for Inflammatory Pain Therapy.
Author: DingJinsong, HouZhiyuan, WenQiang, YanPeng, ZhangHailong, ZhouWenhu
Original Abstract of the Article :
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been widely used in the treatment of inflammatory pain, such as in osteoarthritis. Ketorolac tromethamine is considered to be an NSAID with strong anti-inflammatory and analgesic potency, however, traditional applications, such as oral administratio...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223623/
データ提供:米国国立医学図書館(NLM)
Topical Ketorolac for Inflammatory Pain: A New Oasis of Relief
This research explores a novel approach to [inflammatory pain] treatment using [topical delivery of ketorolac tromethamine] via a [cataplasm]. Traditional methods of [ketorolac] administration often lead to [systemic side effects], such as [gastric ulceration]. This study aimed to develop a [topical delivery system] that could deliver the drug directly to the site of pain, minimizing systemic exposure. The authors designed a [cataplasm] based on a [three-dimensional mesh structure] and tested its efficacy in a [rat model of inflammatory pain]. The results showed that the [cataplasm] delivered [comparable anti-inflammatory and analgesic effects] to [oral administration] while reducing [systemic drug exposure] and [side effects].
A Desert Oasis of Pain Relief: Topical Delivery Takes Center Stage
This research demonstrates the potential of [topical delivery] for [pain relief], offering a less invasive and potentially safer alternative to traditional methods. This is like finding a hidden oasis in the desert - a source of relief and healing, tucked away from the harsh environment of systemic drug delivery. This study highlights the potential for [topical drug delivery] to revolutionize pain management.
Navigating the Desert of Pain: A New Approach
This research opens up new avenues for exploring [topical drug delivery] as a means of addressing [inflammatory pain]. It offers a promising approach that could improve patient outcomes and reduce the risk of [systemic side effects]. This innovative approach is a welcome addition to the landscape of pain management, offering a new oasis of hope in the desert of chronic pain.
Dr.Camel's Conclusion
This study presents a promising new strategy for [inflammatory pain] management. By delivering [ketorolac] topically through a [cataplasm], the authors have effectively minimized [systemic side effects], creating a safer and potentially more effective treatment option. It is a testament to the constant pursuit of innovation in pain management, seeking new oases of relief in the vast desert of chronic pain.
Date :
- Date Completed n.d.
- Date Revised 2023-05-30
Further Info :
Related Literature
English
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