Sirolimus Induced Toxic Optic Neuropathy.

Author: LamByron L, MiriShahnaz, PakravanParastou

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To describe a case of optic neuropathy after prolonged sirolimus therapy in the setting of cardiac transplant. BACKGROUND: Sirolimus is an immunosuppressant that inhibits Mechanistic Target of Rapamycin (mTOR) and blocks T-cell activation and B-cell differentiation by preventing response...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239645/

データ提供:米国国立医学図書館(NLM)

Sirolimus and Optic Neuropathy: A Cautionary Tale

The world of [immunosuppressant drugs] is a complex one, often balancing the need to suppress the immune system with the potential for side effects. This case report focuses on a specific immunosuppressant, [sirolimus], and its potential to cause [optic neuropathy], a condition that can lead to vision loss. Researchers, like detectives investigating a puzzling case, are piecing together the clues to understand the relationship between [sirolimus] and [optic neuropathy].

A Rare but Serious Side Effect

The case report describes a patient who developed [optic neuropathy] after prolonged treatment with [sirolimus], a rare but serious side effect. This highlights the importance of close monitoring for potential complications when using [immunosuppressant drugs]. The researchers also note that [sirolimus] may interact with other medications, potentially increasing the risk of [optic neuropathy].

Navigating the Desert of Side Effects

This case report serves as a reminder that even seemingly safe medications can have unexpected side effects. It underscores the importance of carefully monitoring patients for potential complications and being prepared to adjust treatment regimens when necessary. The researchers emphasize that further research is needed to fully understand the relationship between [sirolimus] and [optic neuropathy].

Dr.Camel's Conclusion

Sirolimus, like a desert mirage, can sometimes appear harmless, but its potential to cause [optic neuropathy] is a reminder that even seemingly safe medications can have unexpected side effects. This case report underscores the importance of vigilance and careful monitoring when prescribing [immunosuppressant drugs].

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-06-08
Further Info :

Pubmed ID

37284436

DOI: Digital Object Identifier

PMC10239645

Related Literature

SNS
PICO Info
in preparation
Languages

English

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