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Original Abstract of the Article :
OBJECTIVE: To describe a case of optic neuropathy after prolonged sirolimus therapy in the setting of cardiac transplant. BACKGROUND: Sirolimus is an immunosuppressant that inhibits Mechanistic Target of Rapamycin (mTOR) and blocks T-cell activation and B-cell differentiation by preventing response...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10239645/
データ提供:米国国立医学図書館(NLM)
Sirolimus and Optic Neuropathy: A Cautionary Tale
The world of [immunosuppressant drugs] is a complex one, often balancing the need to suppress the immune system with the potential for side effects. This case report focuses on a specific immunosuppressant, [sirolimus], and its potential to cause [optic neuropathy], a condition that can lead to vision loss. Researchers, like detectives investigating a puzzling case, are piecing together the clues to understand the relationship between [sirolimus] and [optic neuropathy].
A Rare but Serious Side Effect
The case report describes a patient who developed [optic neuropathy] after prolonged treatment with [sirolimus], a rare but serious side effect. This highlights the importance of close monitoring for potential complications when using [immunosuppressant drugs]. The researchers also note that [sirolimus] may interact with other medications, potentially increasing the risk of [optic neuropathy].
Navigating the Desert of Side Effects
This case report serves as a reminder that even seemingly safe medications can have unexpected side effects. It underscores the importance of carefully monitoring patients for potential complications and being prepared to adjust treatment regimens when necessary. The researchers emphasize that further research is needed to fully understand the relationship between [sirolimus] and [optic neuropathy].
Dr.Camel's Conclusion
Sirolimus, like a desert mirage, can sometimes appear harmless, but its potential to cause [optic neuropathy] is a reminder that even seemingly safe medications can have unexpected side effects. This case report underscores the importance of vigilance and careful monitoring when prescribing [immunosuppressant drugs].
Date :
- Date Completed n.d.
- Date Revised 2023-06-08
Further Info :
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