Doravirine plus lamivudine two-drug regimen as maintenance antiretroviral therapy in people living with HIV: a French observational study.

Author: , AbdiBasma, ArvieuxCédric, DutheJean-Charles, HallNolwenn, KatlamaChristine, LamauryIsabelle, MarcelinAnne-Geneviève, MenardAmélie, PalichRomain, PerfezouPascale, SeangSophie

Paper Details 
Original Abstract of the Article :
Two-drug regimens based on integrase strand transfer inhibitors (INSTIs) and boosted PIs have entered recommended ART. However, INSTIs and boosted PIs may not be suitable for all patients. We aimed to report our experience with doravirine/lamivudine as maintenance therapy in people living with HIV (...See full text at original site
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引用元:
https://doi.org/10.1093/jac/dkad185

データ提供:米国国立医学図書館(NLM)

A New Path in the Desert of HIV Treatment

The world of HIV treatment is a vast and ever-evolving desert, where researchers are constantly seeking new oases of hope. This observational study, like a determined caravan navigating the shifting sands, explores the use of a doravirine/lamivudine two-drug regimen as maintenance antiretroviral therapy for people living with HIV (PLWH). The authors recognize the limitations of existing regimens, particularly for patients who cannot tolerate integrase strand transfer inhibitors (INSTIs) or boosted protease inhibitors (PIs), and seek to evaluate the effectiveness of this alternative approach. The study examines the real-world experience of PLWH followed in French HIV settings.

A Promising Oasis in the Desert of HIV Treatment

This study, like a well-preserved map, provides valuable insights into the potential of doravirine/lamivudine as maintenance therapy for PLWH. While further research is needed to confirm its long-term efficacy and safety, the study's findings offer a promising alternative for patients who cannot tolerate other treatment options. This research, like a refreshing spring in the desert, offers a beacon of hope for those seeking effective and tolerable HIV treatment.

Navigating the Desert of HIV Management

The desert of HIV management continues to evolve, and we must adapt our approaches to provide the most effective care for all patients. This study emphasizes the importance of exploring diverse treatment options, considering individual patient needs and preferences. We must continue our journey through the desert of HIV research, seeking new oases of hope and more personalized approaches to treatment.

Dr.Camel's Conclusion

This study offers a promising glimpse into the potential of doravirine/lamivudine as a maintenance therapy for people living with HIV. It highlights the importance of seeking alternative treatment options and underscores the need for ongoing research to develop individualized and effective therapies.

Date :
  1. Date Completed 2023-08-03
  2. Date Revised 2023-10-12
Further Info :

Pubmed ID

37303236

DOI: Digital Object Identifier

10.1093/jac/dkad185

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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