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Macular Hole in a patient with Pentosan Polysulfate Maculopathy.

Author: AroraNeha, HoyekSandra, PatelNimesh A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Pentosan polysulfate (PPS)-related maculopathy can lead to severe retinal atrophy and a subsequent degenerative macular hole, highlighting the importance of early detection and drug cessation.
Paper Details　
Original Abstract of the Article :
PURPOSE: Pentosan polysulfate (PPS), a drug used for interstitial cystitis, has recently been detected to cause maculopathy in a dose-dependent manner. Outer retinal atrophy is the hallmark of this condition. METHODS: History, examination, and multimodal imaging were used to guide diagnosis and man...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/37321232

データ提供：米国国立医学図書館（NLM）

Pentosan Polysulfate Maculopathy: A Rare Side Effect with Severe Consequences

Pentosan polysulfate (PPS), a medication used to treat interstitial cystitis, has been linked to a rare but serious side effect called maculopathy, which can lead to vision loss. This case report describes a patient who developed PPS-related maculopathy, including a macular hole, highlighting the potential risks associated with this medication.

The Devastating Impact of PPS-Related Maculopathy

This case report highlights the severe consequences of PPS-related maculopathy. The patient experienced significant retinal atrophy and the development of a macular hole, resulting in irreversible vision loss. This case underscores the importance of recognizing the potential risks associated with PPS and carefully monitoring patients who are prescribed this medication. It's like a desert mirage, appearing beautiful but ultimately leading to a potentially disastrous outcome.

A Cautionary Tale: Weighing Risks and Benefits

This case report serves as a cautionary tale, reminding us that even seemingly safe medications can have unforeseen side effects. It emphasizes the importance of carefully weighing the potential risks and benefits of any medication, especially those that have been linked to rare but serious complications. It's like navigating a treacherous desert path, where even a small misstep can have significant consequences.

Dr.Camel's Conclusion

This case report highlights the importance of careful monitoring and early detection of potential side effects associated with medications. It underscores the need for a thorough understanding of the risks and benefits of any medication, particularly those that have been linked to rare but potentially debilitating complications.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-06-15
Further Info :

Pubmed ID

37321232

DOI: Digital Object Identifier

01271216-990000000-00179

Related Literature

Article Analysis
・Effects of pentosan polysulfate
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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