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Integrating 3HP-based tuberculosis preventive treatment into Zimbabwe's Fast Track HIV treatment model: experiences from a pilot study.

Author: ApolloTsitsi, GwanzuraClorata, Hirsch-MovermanYael, HowardAndrea A, MakoniTatenda, MapingureMunyaradzi P, MsukwaMartin, MusukaGodfrey N, RabkinMiriam, SandyCharles, ZechJennifer M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study evaluated the feasibility and acceptability of utilizing the Fast Track (FT) model to deliver tuberculosis preventive treatment (TPT) to people living with HIV (PLHIV) in Zimbabwe. The study found that aligning TPT and HIV visits, providing multi-month dispensing of TPT, and using phone-based support were feasible and acceptable.
Paper Details　
Original Abstract of the Article :
Tuberculosis (TB) causes one-third of HIV-related deaths worldwide, making TB preventive treatment (TPT) a critical element of HIV programmes. Approximately 16% of people living with HIV (PLHIV) on antiretrovirals in Zimbabwe are enrolled in the Fast Track (FT) differentiated service delivery model,...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10281638/

データ提供：米国国立医学図書館（NLM）

Integrating TB Preventive Treatment into Zimbabwe's HIV Fast Track Model: A Journey Through the Desert

The fight against tuberculosis (TB) is a relentless struggle, especially for individuals living with HIV. In Zimbabwe, the Fast Track (FT) differentiated service delivery model is being used to deliver antiretroviral therapy to people living with HIV. This pilot study explored the feasibility and acceptability of integrating 3HP (three months of once-weekly rifapentine and isoniazid) for TB preventive treatment (TPT) within this existing framework. The researchers aligned TPT and HIV visits, provided multi-month dispensing of 3HP, and utilized phone-based monitoring and adherence support. The study's findings highlight the potential of integrating 3HP delivery into the FT model, offering a more efficient and effective way to provide TPT to individuals living with HIV.

A New Path: Integrating TB Prevention into HIV Care

This pilot study demonstrates the feasibility and acceptability of integrating 3HP into Zimbabwe's Fast Track model for HIV care, providing a more efficient and accessible approach to TB prevention. The study's findings offer a roadmap for incorporating TPT into existing healthcare systems, potentially leading to a reduction in TB-related deaths among individuals living with HIV.

A Lifeline in the Desert: Protecting Individuals from TB

This research underscores the importance of integrating TB prevention into HIV care programs, particularly for individuals living in high-burden regions like Zimbabwe. By incorporating 3HP into existing healthcare systems, it's possible to provide a lifeline of protection against TB, safeguarding individuals and mitigating the devastating impact of this deadly disease.

Dr.Camel's Conclusion

This pilot study represents a promising step towards improving TB prevention strategies in Zimbabwe. By integrating 3HP delivery into the Fast Track model, the study offers a more efficient and effective approach to protecting individuals living with HIV from the threat of TB.

Date :
  1. Date Completed 2023-06-22
  2. Date Revised 2023-07-01
Further Info :

Pubmed ID

37339341

DOI: Digital Object Identifier

PMC10281638

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Languages

English

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