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A Different Perspective on the Characterization of a New Degradation Product of Flibanserin With HPLC-DAD-ESI-IT-TOF-MSn and Its Pharmaceutical Formulation Analysis With Inter-Laboratory Comparison.
Author: CanNafiz Öncü, GevenAysun, LeventSerkan, ÖzcanSaniye
Original Abstract of the Article :
BACKGROUND: Flibanserin (FLB) was first synthesized as an antidepressant drug; however, due to its enhancing effects on sexual activity, it was approved for treatment of hypoactive sexual desire disorder in women in 2015. OBJECTIVE: The aim of this study was to develop a new and fully validated HPL...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560319/
データ提供:米国国立医学図書館(NLM)
Flibanserin: A New Oasis in the Desert of Female Sexual Health
The desert of female sexual health can be a challenging landscape to navigate, often marked by a lack of understanding and effective treatment options. This research investigates the stability of flibanserin, a drug approved for the treatment of hypoactive sexual desire disorder in women. The authors developed a new and validated HPLC method for analyzing flibanserin and its degradation products, identifying a novel degradation product under oxidative conditions. This study contributes to understanding the stability and potential degradation pathways of flibanserin, further enhancing its safety and efficacy in treating female sexual health.
Flibanserin: A Promising Treatment for Hypoactive Sexual Desire Disorder
This research explores the stability and potential degradation pathways of flibanserin, a drug approved for the treatment of hypoactive sexual desire disorder in women. The authors' findings provide valuable insights into the quality control and potential degradation mechanisms of this medication, paving the way for more effective and safe treatment options for women experiencing this condition.
Navigating the Desert of Female Sexual Health: Finding the Right Path
This research underscores the importance of understanding the stability and degradation pathways of medications used to treat female sexual health. By ensuring the quality and safety of these drugs, healthcare professionals can offer more effective and personalized treatment options, helping women navigate the desert of sexual health with greater confidence.
Dr.Camel's Conclusion
This research provides a valuable oasis of knowledge in the desert of female sexual health. By understanding the stability and degradation pathways of flibanserin, a drug approved for the treatment of hypoactive sexual desire disorder in women, we can ensure its safety and efficacy, offering more effective treatment options for women navigating this challenging landscape.
Date :
- Date Completed 2023-09-13
- Date Revised 2023-10-10
Further Info :
Related Literature
English
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