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Clinical Management of Potential Toxicity of Abemaciclib and Approaches to Ensure Treatment Continuation.

Author: HashishitaHirokazu, KuwaharaSayuri, MaedaHideki, TakadaShinya, TakahashiMasato, TomiokaNobumoto, UmeharaKengo, WatanabeKenichi, YamamotoMitsugu

Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Abemaciclib dose reduction was found to be a significant factor in achieving longer time to treatment failure (TTF) in patients with advanced breast cancer (ABC). The 100 and 200 mg/day abemaciclib groups had significantly longer TTFs than the 300 mg/day group.
Paper Details　
Original Abstract of the Article :
INTRODUCTION: The association between abemaciclib dose reduction and treatment adherence is not clear. In this study, we examined real-world data of Japanese patients with advanced breast cancer (ABC) to determine how abemaciclib dose reduction is related to treatment continuation. METHODS: This re...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505863/

データ提供：米国国立医学図書館（NLM）

Abemaciclib: A Journey Through the Desert of Cancer Treatment

Abemaciclib, a targeted therapy used in treating advanced breast cancer, can cause side effects that necessitate dose reduction. This study examines the relationship between abemaciclib dose reduction and treatment continuation in Japanese patients with advanced breast cancer. The authors discovered a significant link between dose reduction and prolonged treatment time.

Finding a Balance in the Desert of Cancer Treatment: Dose Reduction and Treatment Continuation

This research provides valuable insights into the management of abemaciclib treatment. The authors' findings suggest that dose reduction can be an effective strategy for managing side effects and improving treatment adherence. This approach offers a potential pathway for improving patient outcomes and extending treatment time.

Navigating the Desert of Side Effects: A Collaborative Approach to Treatment

This study emphasizes the importance of a collaborative approach to managing cancer treatment. The authors' findings highlight the need for careful monitoring of side effects, proactive dose adjustments, and open communication between patients and their healthcare providers to ensure optimal treatment outcomes. This research underscores the importance of individualized care in navigating the challenges of cancer treatment.

Dr.Camel's Conclusion

This research offers a valuable roadmap for navigating the complex landscape of abemaciclib treatment. The authors' findings suggest that dose reduction can be an effective strategy for managing side effects and improving treatment continuation. This approach highlights the importance of a collaborative approach to cancer care, with open communication and individualized treatment plans essential for optimizing patient outcomes.

Date :
  1. Date Completed 2023-06-30
  2. Date Revised 2023-09-20
Further Info :

Pubmed ID

37378924

DOI: Digital Object Identifier

PMC10505863

Related Literature

Article Analysis
・Effects of abemaciclib
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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