Current status and future prospects of activated recombinant coagulation factor VIIa, NovoSeven®, in the treatment of haemophilia and rare bleeding disorders.

Author: ShimaMidori

Paper Details 
Original Abstract of the Article :
rFVIIa, a human recombinant activated coagulation factor VII, has been used worldwide for more than two decades for the treatment of bleeding episodes and prevention of bleeding in patients undergoing surgery/invasive procedures with congenital haemophilia A or B with inhibitors (CHwI A or B), acqui...See full text at original site
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引用元:
https://doi.org/10.1007/s00277-023-05287-2

データ提供:米国国立医学図書館(NLM)

Activated Recombinant Coagulation Factor VIIa: An Ongoing Force in the Treatment of Bleeding Disorders

This research explores the world of bleeding disorders, focusing on the continued role of activated recombinant coagulation factor VIIa (rFVIIa), a crucial treatment for patients with various bleeding conditions. Researchers conducted a comprehensive review of existing literature to assess the current status and future prospects of rFVIIa in treating haemophilia and other rare bleeding disorders. They examined the efficacy, safety, and evolving role of this treatment in the context of new therapeutic approaches.

rFVIIa: A Valuable Tool for Managing Bleeding Disorders

The review confirmed the established efficacy and safety of rFVIIa in treating bleeding episodes and preventing bleeding during surgical procedures in patients with various bleeding disorders. Despite the emergence of newer therapies, such as emicizumab, rFVIIa remains a vital treatment option, particularly for breakthrough bleeding or situations where other therapies are ineffective. This underscores the importance of having multiple treatment options available for patients with bleeding disorders.

Navigating the Treatment Landscape

This research highlights the ongoing evolution of treatment strategies for bleeding disorders. It emphasizes the need for careful evaluation of treatment options, taking into account individual patient needs and the changing landscape of available therapies. Just as a desert traveler adapts their route based on the terrain and conditions, healthcare professionals must navigate the evolving treatment options to find the best approach for each patient.

Dr.Camel's Conclusion

This review reaffirms the importance of rFVIIa as a valuable tool for managing bleeding disorders. It's a reminder that research is constantly advancing, leading to new therapies while strengthening the effectiveness of existing ones. As we continue to explore and innovate, we can offer patients with bleeding disorders a brighter and healthier future. It's a journey towards better treatment outcomes, and rFVIIa continues to play a crucial role in this endeavor.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-06-30
Further Info :

Pubmed ID

37391649

DOI: Digital Object Identifier

10.1007/s00277-023-05287-2

Related Literature

SNS
PICO Info
in preparation
Languages

English

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