Lymphadenopathy as a predictor of progression during venetoclax treatment in chronic lymphocytic leukemia. A campus chronic lymphocytic leukemia study.

Author: AngelettiIlaria, AutoreFrancesco, BaratèClaudia, CataniaGioacchino, ChiurazziFederico, CosciaMarta, CuneoAntonio, De PaolisMaria Rosaria, FarinaLucia, FerrariAngela, FoàRobin, FresaAlberto, GatteiValter, GentileMassimo, GiordanoAnnamaria, InnocentiIdanna, LaurentiLuca, LeoneMonica M A, LosetoGiacomo, MalerbaLara, MattielloVeronica, MoiaRiccardo, PiciocchiAlfonso, QuaresminiGiulia, RedaGianluigi, RigolinGian Matteo, ScortechiniIlaria, SportolettiPaolo, TrentinLivio, VisentinAndrea, VitaleCandida

Paper Details 
Original Abstract of the Article :
Clinical or biological parameters useful to predict progression during treatment in real-life setting with ibrutinib, idelalisib and venetoclax in relapsed/refractory chronic lymphocytic leukemia (CLL) are still debated. We conducted a multi-center retrospective study on CLL patients treated with ib...See full text at original site
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引用元:
https://doi.org/10.1002/hon.3199

データ提供:米国国立医学図書館(NLM)

Lymphadenopathy: A Potential Indicator of Progression in Chronic Lymphocytic Leukemia

Chronic lymphocytic leukemia (CLL), a type of cancer affecting white blood cells, requires careful management to ensure optimal outcomes for patients. This research investigates the potential predictive value of lymphadenopathy, enlarged lymph nodes, in CLL patients undergoing treatment with venetoclax. The study analyzed data from a multi-center retrospective cohort of CLL patients who switched to venetoclax after receiving other treatments. The authors discovered that lymphadenopathy, specifically lymph node diameter greater than 56.5 mm, was an independent risk factor for disease progression during venetoclax treatment. This finding suggests that lymphadenopathy may be a valuable indicator of disease progression in CLL patients, potentially aiding in treatment decisions and monitoring.

Lymphadenopathy: A Potential Signpost in the Desert of CLL

This research offers a new perspective on the management of CLL, highlighting the potential of lymphadenopathy as a predictive indicator of disease progression during venetoclax treatment. This finding, like a signpost in the vast desert of CLL, can help guide healthcare professionals in making informed decisions about treatment strategies and monitoring the course of the disease.

Navigating the Complexities of CLL Treatment

This research underscores the importance of careful monitoring and individualized treatment approaches in managing CLL. The study's findings suggest that lymphadenopathy may be a valuable tool in predicting disease progression, allowing healthcare professionals to tailor treatment plans and monitor patient outcomes more effectively. It's a reminder that navigating the complexities of CLL treatment requires a deep understanding of the disease and its potential indicators, enabling us to provide the best possible care for patients.

Dr.Camel's Conclusion

Just as a wise traveler navigates the desert landscape by paying attention to subtle cues, healthcare professionals can gain valuable insights into the course of CLL by monitoring lymphadenopathy. This research highlights the potential of lymphadenopathy as a predictive indicator of disease progression during venetoclax treatment. It's a reminder that vigilance and careful observation, like looking for signs of life in a seemingly barren desert, can help us make more informed decisions and provide better care for those living with CLL.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-12-10
Further Info :

Pubmed ID

37392141

DOI: Digital Object Identifier

10.1002/hon.3199

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English

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