Considering Sex and Gender in Therapeutics throughout the Product Life Cycle: A Narrative Review and Case Study of Gilteritinib.

Author: BrabeteAndreea, GreavesLorraine, LêMê-Linh, MaximosMira

Paper Details 
Original Abstract of the Article :
Biological sex-related factors influence pharmacokinetic, pharmacodynamic, and disease processes that may affect the predictability of drug dosing and adverse effects, which may in turn have clinical consequences for patients' lives. Nonetheless, sex-related factors are not always taken into account...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10284287/

データ提供:米国国立医学図書館(NLM)

Sex and Gender in Therapeutics: A Journey Through the Desert of Differences

This study delves into the crucial, but often overlooked, topic of sex and gender in drug development and treatment. It's like navigating a vast and often confusing desert, where differences in biology and experiences can significantly impact the effectiveness of medications. The authors are exploring the impact of sex-related factors on the pharmacokinetics, pharmacodynamics, and overall effectiveness of drugs. This research is like a map revealing the diverse landscape of human biology, emphasizing the importance of considering sex and gender in drug development and clinical decision-making. This study is a call for a more inclusive and equitable approach to medicine, recognizing the unique needs and experiences of individuals.

Sex and Gender Matter in Medicine

The study highlights the importance of considering sex and gender in drug development and clinical practice. It's like understanding the different paths through a desert—each requiring a unique strategy for success. This research underscores the need for more research and clinical trials that are designed to accurately assess the impact of sex and gender on drug effectiveness and safety. This research is a reminder that a one-size-fits-all approach to medicine is not always effective or fair.

Building a More Equitable Future for Medicine

This study advocates for a more inclusive and equitable approach to medicine, where the unique needs of individuals are recognized and addressed. It's like creating a more accessible and inclusive desert oasis, where everyone can thrive. This research emphasizes the importance of continuous research and advocacy to ensure that medical advancements benefit all individuals, regardless of their sex or gender.

Dr.Camel's Conclusion

This study is a crucial step towards a more equitable and personalized approach to medicine. It's like recognizing the diversity of desert landscapes—each with its own unique challenges and opportunities. This research highlights the need for a deeper understanding of human biology and a commitment to developing treatments that are effective and safe for all individuals.

Date :
  1. Date Completed n.d.
  2. Date Revised 2023-07-18
Further Info :

Pubmed ID

37409151

DOI: Digital Object Identifier

PMC10284287

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.