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Health care resource utilization in 3L + patients with chronic phase chronic myeloid leukemia receiving asciminib or bosutinib.
Author: CortesJorge E, JadhavKejal, MauroMichael J, ReaDelphine, SasakiKoji, TranDiana, WangPearl, YocollyAurore
Original Abstract of the Article :
OBJECTIVES: To assess and compare health care resource utilization (HCRU) rates of asciminib and bosutinib at the Week 24, Week 48, and Week 96 cutoffs among 3 L + patients with chronic myeloid leukemia in chronic phase (CML-CP) in the randomized ASCEMBL trial. METHODS: Patients in the ASCEMBL tria...See full text at original site
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引用元:
https://doi.org/10.1080/13696998.2023.2234776
データ提供:米国国立医学図書館(NLM)
Asciminib: A Potential Oasis in the Desert of Chronic Myeloid Leukemia Treatment
Chronic myeloid leukemia (CML), a type of blood cancer, presents a challenging landscape for patients and their healthcare providers. This research investigates the impact of asciminib, a tyrosine kinase inhibitor, on health care resource utilization (HCRU) in patients with CML in chronic phase (CML-CP) who have received at least three prior therapies. The study compared HCRU rates between asciminib and bosutinib, another tyrosine kinase inhibitor, in patients enrolled in the ASCEMBL trial. HCRU included hospitalizations, emergency room visits, general practitioner visits, specialist visits, and urgent care visits.
Navigating the Desert: A Comparison of Tyrosine Kinase Inhibitors
The study found that patients treated with asciminib had significantly lower rates of HCRU compared to those treated with bosutinib. These findings suggest that asciminib may be associated with improved patient outcomes and reduced healthcare resource utilization, potentially leading to cost savings and improved quality of life for patients with CML-CP who have received multiple prior therapies.
Navigating the Desert of CML Treatment: Seeking Effective and Efficient Solutions
This research highlights the potential of asciminib as a valuable treatment option for patients with CML-CP who have received at least three prior therapies. It encourages further investigation into the long-term benefits and cost-effectiveness of asciminib, seeking to optimize treatment strategies and minimize the impact of CML on patients' lives. The study underscores the importance of considering both clinical outcomes and healthcare resource utilization when evaluating new treatment options, emphasizing the need for comprehensive and cost-effective approaches to managing chronic diseases.
Dr.Camel's Conclusion
This research offers a valuable perspective on the treatment of chronic myeloid leukemia, highlighting the potential of asciminib to improve patient outcomes and reduce healthcare resource utilization. Like a camel seeking the most efficient route through a desert, we must continually seek innovative and effective treatments for chronic diseases. This study provides a roadmap for navigating the complexities of CML treatment, emphasizing the importance of considering both clinical outcomes and cost-effectiveness in guiding our approach to patient care.
Date :
- Date Completed 2023-07-19
- Date Revised 2023-07-19
Further Info :
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