The Neuropsychiatric Safety Profile of Lasmiditan: A Comparative Disproportionality Analysis with Triptans.

Author: DestereAlexandre, DriciMilou-Daniel, GérardAlexandre O, Lanteri-MinetMichel, MerinoDiane, Van ObberghenElise K

Paper Details 
Original Abstract of the Article :
Migraine constitutes the world's second-leading cause of disability. Triptans, as serotonin 5-HT<sub>1B/1D</sub> receptor agonists, remain the first-line treatment, despite discouraged use in individuals at high cardiovascular risk. Lasmiditan, a selective lipophilic 5-HT<sub>1F</sub> agonist withou...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480366/

データ提供:米国国立医学図書館(NLM)

Lasmiditan: A New Oasis in the Desert of Migraine Treatment

The desert of migraine, like a vast and unforgiving landscape, is a place where millions struggle to find relief. This study, like a group of researchers seeking a new route through the desert, evaluates the safety profile of lasmiditan, a promising new treatment for migraine. The researchers, like skilled desert guides, compare the neuropsychiatric safety profile of lasmiditan to that of triptans, long-standing migraine medications.

Lasmiditan: Navigating the Desert with Caution

This study's findings, like a cautious approach to desert travel, reveal that while lasmiditan appears to be a safe and effective alternative to triptans for migraine treatment, it is not without its own set of neuropsychiatric side effects. The researchers, like meticulous desert explorers, highlight the need for careful consideration when prescribing lasmiditan, particularly for patients with pre-existing neurological or psychiatric conditions.

Living with Migraine: Choosing the Right Path

This research, like a guidebook for navigating the desert, offers valuable insights for individuals seeking relief from migraine. The study's findings, like a well-worn path through the desert, emphasize the importance of a thoughtful approach to migraine treatment, taking into account both the potential benefits and risks of different medications.

Dr. Camel's Conclusion

The study's findings, like a map leading to a hidden oasis, suggest that lasmiditan may offer a safer and more effective alternative to triptans for migraine treatment. However, as with any desert journey, caution is advised, and patients should discuss their individual needs and risks with their healthcare providers to determine the best course of treatment.

Date :
  1. Date Completed 2023-09-07
  2. Date Revised 2023-09-24
Further Info :

Pubmed ID

37436579

DOI: Digital Object Identifier

PMC10480366

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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