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Recent advancements in the targeted delivery of etoposide nanomedicine for cancer therapy: A comprehensive review.

Author: ArshadRabia, BehzadmehrRazieh, Fathi-KarkanSonia, GhotekarSuresh, PandeySadanand, RahdarAbbas, RamezaniAghdas

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This article reviews the progress in developing etoposide nanomedicine for cancer treatment, discussing various nanostructures and their advantages in overcoming limitations of conventional etoposide therapy.
Paper Details　
Original Abstract of the Article :
Etoposide (ETO), a popular anticancer drug that inhibits topoisomerase II enzymes, may be administered more effectively and efficiently due to nanomedicine. The therapeutic application of ETO is constrained by its limited solubility, weak absorption, and severe side effects. This article summarizes ...See full text at original site
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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引用元：
https://doi.org/10.1016/j.ejmech.2023.115676

データ提供：米国国立医学図書館（NLM）

Etoposide Nanomedicine: A New Frontier in Cancer Therapy

The fight against cancer is a relentless quest, and researchers are constantly searching for more effective and targeted therapies. This comprehensive review examines the potential of etoposide (ETO) nanomedicine as a promising approach to cancer treatment. The authors discuss various nanostructures, including lipids, liposomes, polymeric nanoparticles, dendrimers, micelles, and gold, iron oxide, and silica nanoparticles, that can be utilized to deliver ETO more effectively, minimizing side effects and enhancing therapeutic efficacy.

A New Oasis: Nanomedicine for Targeted Cancer Therapy

The desert of cancer research is vast, but nanomedicine offers a new oasis of hope. By encapsulating ETO within nanostructures, researchers can overcome its limitations, such as poor solubility and bioavailability, while achieving more targeted delivery to tumor cells, minimizing damage to healthy tissues.

A Precision Strike: Harnessing the Power of Nanomedicine

This review highlights the potential of nanomedicine to revolutionize cancer treatment, offering a more precise and targeted approach. By harnessing the power of nanotechnology, we can navigate the complexities of cancer with greater precision, delivering therapies more effectively and minimizing the collateral damage associated with conventional treatments.

Dr.Camel's Conclusion

This research, like a caravan venturing into uncharted territory, explores the exciting possibilities of etoposide nanomedicine. By embracing the power of nanotechnology, we can create a more effective and targeted approach to cancer therapy, potentially changing the landscape of this formidable disease.

Date :
  1. Date Completed 2023-08-22
  2. Date Revised 2023-08-22
Further Info :

Pubmed ID

37499287

DOI: Digital Object Identifier

10.1016/j.ejmech.2023.115676

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・Side Effects of etoposide
SNS
PICO Info
in preparation
Languages

English

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